反应条件
1: 1-bromo-3-methyl-benzene With tert.-butyl lithium in n-heptane; anhydrous butyl ether
T=-10 - 20°C; Inert atmosphereSchlenk technique;
2: With DABCO-bis(sulfur dioxide) in 1,4-dioxane; n-heptane; anhydrous butyl ether
T=20°C; 2 h; Inert atmosphereSchlenk technique;
3: p-trifluoromethanesulfonyloxytoluene With potassium phosphate; palladium diacetate; (9,9-dimethyl-9H-xanthene-4,5-diyl)bis(bis(3,5-bis(trifluoromethyl)phenyl)phosphine) in 1,4-dioxane; n-heptane; anhydrous butyl ether
T=110°C; 16 h; Inert atmosphereSchlenk techniqueSealed tube;
参考文献
Emmett, Edward J.; Hayter, Barry R.; Willis, Michael C.
Angewandte Chemie - International Edition, 2013 , vol. 52, # 48 p. 12679 - 12683
Angew. Chem., 2013 , vol. 125, # 48 p. 12911 - 12915,5
