反式-4-氧基-2-丁烯酸乙酯合成路线 （共 44 条）
参考文献
Devos,M.J. et al.
Tetrahedron Letters, 1976 , p. 3911 - 3914
反应条件
1: 94 percent / CaCl2 / 72 h / Ambient temperature
2: 1.) NaH / 1.) DMSO, 2.) 2 h
3: 93 percent / H2SO4 / H2O / 3 h
4: 52 percent / conc. HCl / diethyl ether / 6 h / 0 °C
View Scheme
参考文献
Landor, Stephen R.; Landor, Phyllis, D.; Kalli, Michael
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 12 p. 2921 - 2926
反应条件
1.1: Pearlman's catalist; hydrogen / ethyl acetate / 9 h
2.1: n-butyllithium / tetrahydrofuran; hexanes / 1 h
2.2: 5 h / 21 °C
View Scheme
参考文献
Izquierdo, Javier; Rodriguez, Santiago; Gonzalez, Florenci V.
Organic Letters, 2011 , vol. 13, # 15 p. 3856 - 3859
反应条件
n-butyllithium in tetrahydrofuran; hexane
1) -20 deg C, 2) r.t., 2 h;
参考文献
Steroids, 1983 , vol. 41, # 3 p. 277 - 284
