2-邻甲苯-1H-苯并咪唑合成路线 （共 22 条）
反应条件
potassium tert-butylate in N,N-dimethyl acetamide
T=120°C; 24 h; Schlenk techniqueInert atmosphere;
参考文献
Xiang, Shi-Kai; Tan, Wen; Zhang, Dong-Xue; Tian, Xian-Li; Feng, Chun; Wang, Bi-Qin; Zhao, Ke-Qing; Hu, Ping; Yang, Hua
Organic and Biomolecular Chemistry, 2013 , vol. 11, # 42 p. 7271 - 7275
反应条件
dioxygen-CuCl-pyridine in pyridine
参考文献
Speier, Gabor; Parkanyi, Laszlo
Journal of Organic Chemistry, 1986 , vol. 51, # 2 p. 218 - 221
反应条件
1: 89 percent Chromat. / 3 Angstroem molecular sieves; DBU; carbon monoxide / Se / dioxane / 3 h / 120 °C / 22800 Torr
View Scheme
参考文献
Nishiyama, Yutaka; Fujimoto, Mayu; Sonoda, Noboru
Synlett, 2006 , # 1 art. no. U26605ST, p. 109 - 111
反应条件
FeBr2 in dichloromethane
T=40°C; 12 h; Inert atmosphereMolecular sieve;
参考文献
Shen, Meihua; Driver, Tom G.
Organic Letters, 2008 , vol. 10, # 15 p. 3367 - 3370
反应条件
phosphoric acid
T=150°C; 0.25 h; Microwave irradiation;
参考文献
Zhang, Tao; Huang, Liang-Zhu; Wu, Jia; Lu, Dong; Ma, Bo-Lin; Du, Zhen-Ting
Heterocycles, 2013 , vol. 87, # 7 p. 1545 - 1552
反应条件
copper(I) oxide; potassium carbonate; N-methyl-2-(methylamino)ethylamine in water
T=100°C; 30 h; Sealed tube;
参考文献
Peng, Jinsong; Ye, Min; Zong, Cuijuan; Hu, Fangyun; Feng, Lingtong; Wang, Xiaoyan; Wang, Yufeng; Chen, Chunxia
Journal of Organic Chemistry, 2011 , vol. 76, # 2 p. 716 - 719
反应条件
1: 89 percent Chromat. / 3 Angstroem molecular sieves; DBU; carbon monoxide / Se / dioxane / 3 h / 120 °C / 22800 Torr
View Scheme
参考文献
Nishiyama, Yutaka; Fujimoto, Mayu; Sonoda, Noboru
Synlett, 2006 , # 1 art. no. U26605ST, p. 109 - 111
反应条件
1: 92 percent / pyridine / tetrahydrofuran / 5 h / Ambient temperature
2: 78 percent / Fe, glacial acetic acid / 0.5 h / Heating
View Scheme
参考文献
Roth, Thomas; Morningstar, Marshall L.; Boyer, Paul L.; Hughes, Stephen H.; Buckheit Jr., Robert W.; Michejda, Christopher J.
Journal of Medicinal Chemistry, 1997 , vol. 40, # 26 p. 4199 - 4207
参考文献
Ramana, Devalla V.; Kantharaj, Ethirajulu
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1995 , # 7 p. 1497 - 1502
反应条件
diethyl ether
T=-15°C;
参考文献
Wuyts; van Vaerenbergh
Bulletin des Societes Chimiques Belges, 1939 , vol. 48, p. 329,335
