2-氟-4-碘苯胺合成路线

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Kruger; Keck; Noll; Pieper
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NOVARTIS AG; BOCK, Mark G.; CHIKKANNA, Dinesh; MCCARTHY, Clive; MOEBITZ, Henrik; PANDIT, Chetan; PODDUTOORI, Ramulu
Patent: WO2011/70030 A1, 2011 ;
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29632-74-42-氟-4-碘苯胺

93129-68-1N-(4-氰基-2-氟苯基)乙酰胺

参考文献

Kruger; Keck; Noll; Pieper
Arzneimittel-Forschung/Drug Research, 1984 , vol. 34, # 11 A p. 1612 - 1624

28314-80-92,4,6-三氟苯甲酸+

29632-74-42-氟-4-碘苯胺

934665-14-22,4-二氟-6-[(2-氟-4-碘苯基)氨基]苯甲酸

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EXELIXIS, INC.
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29632-74-42-氟-4-碘苯胺+

108-24-7乙酸酐

97760-94-6N-(2-氟-4-碘苯基)乙酰氨

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Hoffmann-La Roche Inc.
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29632-74-42-氟-4-碘苯胺

97760-94-6N-(2-氟-4-碘苯基)乙酰氨

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Sidduri, Achyutharao
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29632-74-42-氟-4-碘苯胺+

75-36-5乙酰氯

97760-94-6N-(2-氟-4-碘苯基)乙酰氨

参考文献

Suh, Young-Ger; Lee, Yong-Sil; Min, Kyung-Hoon; Park, Ok-Hui; Kim, Jin-Kwan; Seung, Ho-Sun; Seo, Seung-Yong; Lee, Bo-Young; Nam, Yeon-Hee; Lee, Kwang-Ok; Kim, Hee-Doo; Park, Hyeung-Geun; Lee, Jeewoo; Oh, Uhtaek; Lim, Ju-Ok; Kang, Sang-Uk; Kil, Min-Jung; Koo, Jae-Yeon; Shin, Song Seok; Joo, Yung-Hyup; Kim, Jin Kwan; Jeong, Yeon-Su; Kim, Sun-Young; Park, Young-Ho
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142-08-52-羟基吡啶+

29632-74-42-氟-4-碘苯胺

536747-52-11-(4-氨基-3-氟苯基)吡啶-2(1h)-酮

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MILLENNIUM PHARMACEUTICALS, INC.; SCARBOROUGH, Carroll
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WO 2008/086226 A2

675-20-72-氮己环酮+

29632-74-42-氟-4-碘苯胺

536747-52-11-(4-氨基-3-氟苯基)吡啶-2(1h)-酮

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WARNER-LAMBERT COMPANY LLC
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WO 2006/100565 A1

142-08-52-羟基吡啶+

148-24-38-羟基喹啉

536747-52-11-(4-氨基-3-氟苯基)吡啶-2(1h)-酮

参考文献

Bigge, Christopher Franklin; Casimiro-Garcia, Agustin; Dudley, Danette Andrea; Edmunds, Jeremy John; Filipski, Kevin James; Kohrt, Jeffrey Thomas; Van Huis, Chad Alan
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