5-溴-1,2-苯异噻唑-3(2H)-酮 1,1-二氧化物合成路线 （共 4 条）
反应条件
1: With hydrogenchloride; sodium nitrite in water T=0 - 5°C; 0.75 h; 2: With sulfur dioxide; copper(l) chloride in water; acetic acid 3: With ammonia in methanol T=10 - 20°C; 1 h;
参考文献
Hadida Ruah, Sara S.; Miller, Mark T.; Bear, Brian; McCartney, Jason; Grootenhuis, Peter D. J.
Patent: US2008/9524 A1, 2008 ;
Location in patent: Page/Page column 410-411 ;
反应条件
ammonia; acetic acid; sodium nitrite in tetrahydrofuran; hydrogenchloride; methanol; water; sodium hydrogencarbonate
参考文献
Vertex Pharmaceuticals Incorported
Patent: US2011/98311 A1, 2011 ;
反应条件
chromium(VI) oxide; periodic acid in acetonitrile 1 h; Heating;
参考文献
Xu, Liang; Shu, Hong; Liu, Ying; Zhang, Suhong; Trudell, Mark L.
Tetrahedron, 2006 , vol. 62, # 33 p. 7902 - 7910
参考文献
Yagupol'skii,L.M. et al.
Journal of Organic Chemistry USSR (English Translation), 1970 , vol. 6, p. 1694 - 1696
Zhurnal Organicheskoi Khimii, 1970 , vol. 6, p. 1689 - 1692
