4-羟甲基-5-甲基咪唑合成路线 （共 11 条）
反应条件
hydrogenchloride in tetrahydrofuran; ethanol
反应条件
sodium hydroxide in water 0.5 h; Heating;
参考文献
Journal of Heterocyclic Chemistry, , vol. 20, p. 1417 - 1418
参考文献
Journal of Medicinal Chemistry, , vol. 45, # 17 p. 3721 - 3738
反应条件
triethylamine in N,N-dimethyl-formamide 16 h; Ambient temperature;
参考文献
Cordi; Snyers; Giraud-Mangin; Van der Maesen; Van Hoeck; Beuze; Ellens; Napora; Gillet; Gorissen; Calderon; Remacle; Janssens de Varebeke; Van Dorsser; Roba
European Journal of Medicinal Chemistry, 1990 , vol. 25, # 7 p. 557 - 568
反应条件
manganese(IV) oxide; sodium cyanide T=20°C; Oxidation; esterification; 20 h;
参考文献
Figueiredo, Juliana M.; Camara, Celso De A.; Amarante, Emanuel G.; Miranda, Ana Luisa P.; Santos, Fulvia M.; Rodrigues, Carlos R.; Fraga, Carlos Alberto M.; Barreiro, Eliezer J.
Bioorganic and Medicinal Chemistry, 2000 , vol. 8, # 9 p. 2243 - 2248
反应条件
manganese(IV) oxide in tetrahydrofuran Oxidation; 3 h; Heating;
参考文献
Figueiredo, Juliana M.; Camara, Celso De A.; Amarante, Emanuel G.; Miranda, Ana Luisa P.; Santos, Fulvia M.; Rodrigues, Carlos R.; Fraga, Carlos Alberto M.; Barreiro, Eliezer J.
Bioorganic and Medicinal Chemistry, 2000 , vol. 8, # 9 p. 2243 - 2248
反应条件
acetic acid Heating;
参考文献
Synthetic Communications, , vol. 18, # 13 p. 1581 - 1588
反应条件
1: Et3N / dimethylformamide 2: 80 percent / SOCl2 / dimethylformamide; CH2Cl2 / 0.25 h / 0 °C View Scheme
参考文献
Cordi; Snyers; Giraud-Mangin; Van der Maesen; Van Hoeck; Beuze; Ellens; Napora; Gillet; Gorissen; Calderon; Remacle; Janssens de Varebeke; Van Dorsser; Roba
European Journal of Medicinal Chemistry, 1990 , vol. 25, # 7 p. 557 - 568
反应条件
sodium tetrahydroborate; 1 Pd/C; water; potassium hydroxide in methanol T=20°C; 19 h; In air;
参考文献
An, Gwangil; Ahn, Hyunseok; De Castro, Kathlia A.; Rhee, Hakjune
Synthesis, 2010 , # 3 art. no. F19009SS, p. 477 - 485
反应条件
Ambient temperature;
参考文献
Harper, Jacquie L.; Smith, Robin A. J.; Bedford, Jennifer J.; Leader, John P.
Tetrahedron, 1997 , vol. 53, # 24 p. 8211 - 8224
