3-溴-2-氯-6-硝基-喹啉合成路线 (共 3 条)
反应条件
trichlorophosphate in N,N-dimethyl-formamide T=100°C; Chlorination; 0.5 h;
参考文献
Lee, Byoung Se; Chu, Soyoung; Lee, Byung Chul; Chi, Dae Yoon; Choe, Yearn Seong; Jeong, Kyung Ja; Jin, Changbae
Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 14 p. 1559 - 1562
反应条件
1: 76 percent / aq. NaBrO3; HBr / 4 h / 100 °C 2: 93 percent / POCl3 / dimethylformamide / 0.5 h / 100 °C View Scheme
参考文献
Lee, Byoung Se; Chu, Soyoung; Lee, Byung Chul; Chi, Dae Yoon; Choe, Yearn Seong; Jeong, Kyung Ja; Jin, Changbae
Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 14 p. 1559 - 1562
反应条件
1: 99 percent / AcOH / 10 h / 100 °C 2: 76 percent / aq. NaBrO3; HBr / 4 h / 100 °C 3: 93 percent / POCl3 / dimethylformamide / 0.5 h / 100 °C View Scheme
参考文献
Lee, Byoung Se; Chu, Soyoung; Lee, Byung Chul; Chi, Dae Yoon; Choe, Yearn Seong; Jeong, Kyung Ja; Jin, Changbae
Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 14 p. 1559 - 1562