(R)-2-羟基-4-苯基丁酸合成路线 (共 58 条)
反应条件
sulfuric acid; sodium nitrite
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 18, # 14 p. 4210 - 4214
反应条件
palladium on activated charcoal; ethanol Hydrogenation.Erhitzen des Reaktionsprodukts mit wss. HCl;
参考文献
Helvetica Chimica Acta, , vol. 37, p. 1634,1656
反应条件
1: quinine-bis methiodide; triethylamine 2: palladium/charcoal; ethanol / Hydrogenation.Erhitzen des Reaktionsprodukts mit wss. HCl View Scheme
参考文献
Helvetica Chimica Acta, , vol. 37, p. 1634,1656
反应条件
sodium phosphate buffer; octadecyl-Sepabeads-Bacillus thermocatenulatus lipase BTL2 in water T=25°C; pH=7.5; Product distribution; Further Variations:ReagentsTemperaturesSolvents;
参考文献
Tetrahedron Asymmetry, , vol. 14, # 23 p. 3679 - 3687
参考文献
Tetrahedron Letters, , vol. 29, # 4 p. 423-426
反应条件
Enterobacter cloacae P99 β-lactamase T=25°C; pH=7.5; aq. bufferEnzymatic reaction; Kinetics; Reagent/catalystConcentration;
参考文献
Biochemistry, , vol. 49, # 49 p. 10496 - 10506
反应条件
sulfuric acid 16 h; Ambient temperature;
参考文献
Journal of Medicinal Chemistry, , vol. 30, # 11 p. 1984 - 1991
反应条件
hydrogenchloride in ethanol
参考文献
Tetrahedron Letters, , vol. 29, # 4 p. 423-426
参考文献
Tetrahedron Letters, , vol. 38, # 9 p. 1593 - 1596
反应条件
1: HCl 2: pyridine / CH2Cl2 / Ambient temperature 3: N(C2H5)3 / CH2Cl2 / Ambient temperature 4: H2 / Pd/C / ethanol / 760 Torr / Ambient temperature View Scheme
参考文献
Urbach, H.; Henning, R.
Tetrahedron Letters, 1984 , vol. 25, # 11 p. 1143 - 1146