1-溴-2-氯-4-硝基苯合成路线 （共 15 条）
反应条件
1: caesium carbonate / toluene / 100 °C / Inert atmosphere
2: tin(ll) chloride / ethanol / 70 °C / Inert atmosphere
View Scheme
参考文献
Steffen, Jamin D.; Coyle, Donna L.; Damodaran, Komath; Beroza, Paul; Jacobson, Myron K.
Journal of Medicinal Chemistry, 2011 , vol. 54, # 15 p. 5403 - 5413
反应条件
1: caesium carbonate / toluene / 100 °C / Inert atmosphere
2: tin(ll) chloride / ethanol / 70 °C / Inert atmosphere
View Scheme
参考文献
Steffen, Jamin D.; Coyle, Donna L.; Damodaran, Komath; Beroza, Paul; Jacobson, Myron K.
Journal of Medicinal Chemistry, 2011 , vol. 54, # 15 p. 5403 - 5413
反应条件
caesium carbonate in toluene
T=100°C; Inert atmosphere;
参考文献
Steffen, Jamin D.; Coyle, Donna L.; Damodaran, Komath; Beroza, Paul; Jacobson, Myron K.
Journal of Medicinal Chemistry, 2011 , vol. 54, # 15 p. 5403 - 5413
反应条件
nitrogen; sodium carbonate in nitrobenzene
参考文献
Ciba-Geigy Corporation
Patent: US4082778 A1, 1978 ;
反应条件
1: caesium carbonate / toluene / 100 °C / Inert atmosphere
2: tin(ll) chloride / ethanol / 70 °C / Inert atmosphere
View Scheme
参考文献
Steffen, Jamin D.; Coyle, Donna L.; Damodaran, Komath; Beroza, Paul; Jacobson, Myron K.
Journal of Medicinal Chemistry, 2011 , vol. 54, # 15 p. 5403 - 5413
