2,4,6-三甲氧基苯甲酸甲酯合成路线 （共 24 条）
反应条件
aluminium trichloride
参考文献
Herzig; Wenzel; Toelk
Monatshefte fuer Chemie, 1902 , vol. 23, p. 95
反应条件
potassium carbonate; acetone
参考文献
Whalley
Journal of the Chemical Society, 1951 , p. 665,669
反应条件
potassium carbonate; acetone
参考文献
Curd; Robertson
Journal of the Chemical Society, 1933 , p. 437,440
参考文献
Balgir,B.S. et al.
Australian Journal of Chemistry, 1973 , vol. 26, p. 2459 - 2472
参考文献
Herzig; Wenzel
Monatshefte fuer Chemie, 1902 , vol. 23, p. 92
参考文献
Curd; Robertson
Journal of the Chemical Society, 1933 , p. 437,440
参考文献
Herzig; Wenzel; Toelk
Monatshefte fuer Chemie, 1902 , vol. 23, p. 95
反应条件
1: 80 percent / BBr3 / CH2Cl2 / 0.67 h / -70 - 20 °C 2: 94 percent / NaH / dimethylformamide / 2 h / 20 °C 3: 85 percent / ZnCl2; Pd2(dba)3; dppf / tetrahydrofuran / 17 h / 0 - 60 °C 4: 67 percent / I2 / acetonitrile / 2 h / 20 °C 5: 98 percent / formic acid; Et3N; PPh3 / Pd(OAc)2 / dimethylformamide / 60 - 63 °C View Scheme
参考文献
Rossi, Renzo; Carpita, Adriano; Bellina, Fabio; Stabile, Paolo; Mannina, Luisa
Tetrahedron, 2003 , vol. 59, # 12 p. 2067 - 2081
反应条件
1: 80 percent / BBr3 / CH2Cl2 / 0.67 h / -70 - 20 °C
2: 94 percent / NaH / dimethylformamide / 2 h / 20 °C
3: 85 percent / ZnCl2; Pd2(dba)3; dppf / tetrahydrofuran / 17 h / 0 - 60 °C
4: 67 percent / I2 / acetonitrile / 2 h / 20 °C
5: 98 percent / formic acid; Et3N; PPh3 / Pd(OAc)2 / dimethylformamide / 60 - 63 °C
6: 81 percent / BBr3 / CH2Cl2 / 72 h / 20 °C
View Scheme
参考文献
Rossi, Renzo; Carpita, Adriano; Bellina, Fabio; Stabile, Paolo; Mannina, Luisa
Tetrahedron, 2003 , vol. 59, # 12 p. 2067 - 2081
反应条件
1: 1-bromo-2,4-dimethoxy-benzene With n-butyllithium in diethyl ether; hexane
T=20°C; 0.166667 h; Inert atmosphere;
2: Methyl2,4,6-trimethoxybenzoate in diethyl ether; hexane
0.05 h; Temperature;
参考文献
INDICATOR SYSTEMS INTERNATIONAL, INC.; SWISS, Gerald F.; RAO, Photon; SABNIS, Ram W.
Patent: WO2013/90682 A1, 2013 ;
Location in patent: Paragraph 0050 ;
