3,5-二溴-4-羟基苯甲醛合成路线 （共 27 条）
反应条件
water in 1,4-dioxane T=34°C; Kinetics;
参考文献
Tetrahedron Letters, , vol. 23, # 12 p. 1305 - 1308
反应条件
anschliessend mit Brom in wss.HCl;
参考文献
Pharmazie, , vol. 12, p. 647,649,650
反应条件
sodium tetrahydroborate in ethanol T=20°C; Inert atmosphere;
参考文献
Akai, Shuji; Ikawa, Takashi; Takayanagi, Sho-Ichi; Morikawa, Yuki; Mohri, Shinya; Tsubakiyama, Masaya; Egi, Masahiro; Wada, Yasufumi; Kita, Yasuyuki
Angewandte Chemie - International Edition, 2008 , vol. 47, # 40 p. 7673 - 7676
反应条件
1: 3,5-dibromo-4-hydroxy-benzaldehyde; sodium methylate With copper(l) chloride in methanol; N,N-dimethyl-formamide T=120°C; 3 h; 2: dimethyl sulfate With sodium hydroxide pH=8.5 - 9.3; 3 h;
参考文献
Ji, Ya-Fei; Zong, Zhi-Min; Wei, Xian-Yong
Synthetic Communications, 2002 , vol. 32, # 18 p. 2809 - 2814
反应条件
1: 88 percent / Cu2Cl2 / dimethylformamide / 2.5 h / 97 °C 2: 91.5 percent / Na2CO3, KOH / acetone; H2O / 18 h / Heating View Scheme
参考文献
Manchand, Percy S.; Belica, Peter S.; Wong, Harry S.
Synthetic Communications, 1990 , vol. 20, # 17 p. 2659 - 2666
反应条件
pyridine; hydroxylamine hydrochloride in methanol T=20°C; 24 h;
参考文献
Garcia-Alvarez, Rocio; Diaz-Alvarez, Alba E.; Borge, Javier; Crochet, Pascale; Cadierno, Victorio
Organometallics, 2012 , vol. 31, # 17 p. 6482 - 6490
反应条件
sodium hydride in hexane; N,N-dimethyl-formamide T=20°C; Condensation; 24 h;
参考文献
Itaya, Taisuke; Hozumi, Yoshitaka; Kanai, Tae; Ohta, Tomihisa
Chemical and Pharmaceutical Bulletin, 1999 , vol. 47, # 9 p. 1297 - 1300
参考文献
Buu-Hoi et al.
Journal of Organic Chemistry, 1953 , vol. 18, p. 121,124
反应条件
1: hydroxylamine hydrochloride; pyridine / methanol / 24 h / 20 °C 2: [RuCl2(η2-C6H6){P(NMe2)3}]; water / 7 h / 100 °C / |Inert atmosphere; |Sealed tube View Scheme
参考文献
Garcia-Alvarez, Rocio; Diaz-Alvarez, Alba E.; Borge, Javier; Crochet, Pascale; Cadierno, Victorio
Organometallics, 2012 , vol. 31, # 17 p. 6482 - 6490
反应条件
copper(I) bromide in N,N-dimethyl-formamide
参考文献
Zabinski, Jerzy; Wolska, Irena; Maciejewska, Dorota
Journal of Molecular Structure, 2007 , vol. 833, # 1-3 p. 74 - 81
