3,5-二溴-4-羟基苯甲醛合成路线 （共 27 条）
参考文献
Dakin
American Chemical Journal, 1909 , vol. 42, p. 495
反应条件
1.1: 70.5 percent / K2CO3 / dimethylformamide / 4 h / 100 °C 2.1: 97 percent / NaOAc; Ac2O / 4 h / 120 °C 3.1: aq. Ba(OH)2 / dioxane / 1 h / 60 °C 3.2: 33.5 percent / dioxane / 13 h / 60 °C 4.1: 68 percent / HOBt; DCC; Et3N / dimethylformamide; CHCl3 / 26 h / 20 °C 5.1: AlCl3; anisole / nitromethane; CH2Cl2 / 4 h / 20 °C View Scheme
参考文献
Zhu, Guangyu; Yang, Fanglong; Balachandran, Raghavan; Hoeoek, Peter; Vallee, Richard B.; Curran, Dennis P.; Day, Billy W.
Journal of Medicinal Chemistry, 2006 , vol. 49, # 6 p. 2063 - 2076
反应条件
1-nitroethane; sodium acetate; acetic acid 4 h; Heating;
参考文献
Vidyasagar, A.; Nalawala, K. J.; Varshney, A. K.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1993 , vol. 32, # 8 p. 872 - 873
反应条件
1: 92 percent / CuBr / dimethylformamide
2: 77 percent / NH2OH*HCl; CH3CO2Na/HCO2H
View Scheme
参考文献
Zabinski, Jerzy; Wolska, Irena; Maciejewska, Dorota
Journal of Molecular Structure, 2007 , vol. 833, # 1-3 p. 74 - 81
反应条件
potassium carbonate
6 h; Heating;
参考文献
Mallavadhani, Uppuluri V.; Mahapatra, Anita; Narasimhan; Sahoo
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2002 , vol. 41, # 7 p. 1460 - 1466
反应条件
2: (i) HCl, CH2Cl2, (ii) Et3N
View Scheme
参考文献
Pospisek,J. et al.
Collection of Czechoslovak Chemical Communications, 1975 , vol. 40, p. 142 - 148
参考文献
Papa et al.
Journal of the American Chemical Society, 1950 , vol. 72, p. 4906,4908
