2-羟基-3,5-二硝基吡啶合成路线 （共 17 条）
反应条件
1: phosphoryl chloride; phosphorus (V)-chloride 2: ethanol 3: silver acetate; water View Scheme
参考文献
Plazek
Recueil des Travaux Chimiques des Pays-Bas, 1953 , vol. 72, p. 569,573
反应条件
hydrazine hydrate T=90 - 95°C; 7 h;
参考文献
Yutilov, Yu.M.; Smolyar, N.N.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1986 , vol. 22, # 8 p. 926
Khimiya Geterotsiklicheskikh Soedinenii, 1986 , # 8 p. 1136
反应条件
hydrazine hydrate T=90 - 95°C; 7 h;
参考文献
Yutilov, Yu.M.; Smolyar, N.N.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1986 , vol. 22, # 8 p. 926
Khimiya Geterotsiklicheskikh Soedinenii, 1986 , # 8 p. 1136
反应条件
potassium hydroxide; water und Erhitzen des Reaktionsprodukts mit Methyljodid und Methanol auf 120grad;
参考文献
Berrie et al.
Journal of the Chemical Society, 1951 , p. 2590,2593
反应条件
phosphorus oxytribromide
参考文献
van Ammers; den Hertog
Recueil des Travaux Chimiques des Pays-Bas, 1956 , vol. 75, p. 1259,1261, 1262
反应条件
N,N-dimethyl-formamide; trichlorophosphate T=90 - 100°C; 4 h;
参考文献
Rasheed, Khalid; Warkentin, James D.
Journal of Heterocyclic Chemistry, 1981 , vol. 18, p. 1581 - 1585
参考文献
Austin, Nigel E.; Hadley, Michael S.; Harling, John D.; Harrington, Frank P.; Macdonald, Gregor J.; Mitchell, Darren J.; Riley, Graham J.; Stean, Tania O.; Stemp, Geoffrey; Stratton, Sharon C.; Thompson, Mervyn; Upton, Neil
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 10 p. 1627 - 1629
