4-羟基-4-甲基二苯胺合成路线 （共 17 条）
反应条件
C43H62ClNO2PPd; sodium t-butanolate in 1,4-dioxane T=110°C; 1 h; Inert atmosphere;
参考文献
Maiti, Debabrata; Buchwald, Stephen L.
Journal of the American Chemical Society, 2009 , vol. 131, # 47 p. 17423 - 17429
反应条件
lithium hexamethyldisilazane; Verkade nonionic superbase; palladium diacetate in tetrahydrofuran; toluene T=80°C; 28 h;
参考文献
Urgaonkar, Sameer; Verkade, John G.
Advanced Synthesis and Catalysis, 2004 , vol. 346, # 6 p. 611 - 616
反应条件
copper(l) iodide; potassium carbonate; trans-N,N'-dimethylcyclohexane-1,2-diamine in n-butyronitrile T=70°C; 24 h; Inert atmosphere;
参考文献
Maiti, Debabrata; Buchwald, Stephen L.
Journal of the American Chemical Society, 2009 , vol. 131, # 47 p. 17423 - 17429
反应条件
1: [bis(acetoxy)iodo]benzene / 0.08 h / 25 °C / |Schlenk technique; |Inert atmosphere 2: bismuth trifluoromethanesulphonate / methanol / 25 °C / |Schlenk technique; |Inert atmosphere 3: zinc; trifluoroacetic acid / methanol / 25 °C / |Schlenk technique; |Inert atmosphere View Scheme
参考文献
Zhang, Li; Wang, Weibin; Fan, Renhua
Organic Letters, 2013 , vol. 15, # 8 p. 2018 - 2021
反应条件
1: bismuth trifluoromethanesulphonate / methanol / 25 °C / |Schlenk technique; |Inert atmosphere 2: zinc; trifluoroacetic acid / methanol / 25 °C / |Schlenk technique; |Inert atmosphere View Scheme
参考文献
Zhang, Li; Wang, Weibin; Fan, Renhua
Organic Letters, 2013 , vol. 15, # 8 p. 2018 - 2021
反应条件
hydrogen fluoride; palladium Hydrogenation;
参考文献
Weinmayr
Journal of the American Chemical Society, 1955 , vol. 77, p. 1762
反应条件
zinc(II) chloride T=180°C;
参考文献
Hatschek; Zega
Journal fuer Praktische Chemie (Leipzig), 1886 , vol. <2>33, p. 224
反应条件
in acetic acid T=60°C; Reduction; condensation; addition; cyclization; 3 h; Further byproducts given;
参考文献
Burmistrov; Toropin; Galamai; Likussar; Michelic; Reiner; Schubert-Zilavec
Russian Journal of Organic Chemistry, 1996 , vol. 32, # 8 p. 1231 - 1232
参考文献
Willstaetter; Kubli
Chemische Berichte, 1909 , vol. 42, p. 4163
参考文献
Bamberger; Brun
Helvetica Chimica Acta, 1923 , vol. 6, p. 946,947
Helvetica Chimica Acta, 1924 , vol. 7, p. 112,114
