4-(2-苯基-1-乙炔)苯甲腈合成路线 （共 64 条）
反应条件
1,1'-bis-(diphenylphosphino)ferrocene; cesium fluoride; palladium diacetate in 1-methyl-pyrrolidin-2-one
T=120°C; 12 h;
参考文献
Yamazaki, Osamu; Tanaka, Toshifumi; Shimada, Shigeru; Suzuki, Yohichi; Tanaka, Masato
Synlett, 2004 , # 11 p. 1921 - 1924
反应条件
potassium phosphate; tetrakis(triphenylphosphine) palladium(0) in N,N-dimethyl-formamide
T=90°C; 2 h; Inert atmosphere;
参考文献
Rao, Maddali L. N.; Jadhav, Deepak N.; Dasgupta, Priyabrata
Organic Letters, 2010 , vol. 12, # 9 p. 2048 - 2051
反应条件
1: tri-phenyl-antimony With [bis(acetoxy)iodo]benzene in dichloromethane
T=20°C; 7 h;
2: 4-[2-(trimethylsilyl)ethynyl]benzonitrile With tris(dibenzylideneacetone)dipalladium(0) chloroform complex; copper(l) iodide in acetonitrile
T=50°C; 5 h; Further stages.;
参考文献
Kang, Suk-Ku; Ryu, Hyung-Chul; Hong, Young-Taek
Journal of the Chemical Society. Perkin Transactions 1, 2001 , # 7 p. 736 - 739
反应条件
tetra-(n-butyl)ammonium iodide; (Ph3P)2Pd(Ph)(I) in N,N,N',N',N'',N''-hexamethylphosphoric triamide
T=20°C;
参考文献
Bumagin, N. A.; Kalinovskii, I. O.; Ponomarev, A. B.; Beletskaya, I. P.
Doklady Chemistry, 1982 , vol. 265, p. 262 - 266
Dokl. Akad. Nauk SSSR Ser. Khim., 1982 , vol. 265, # 5 p. 1138 - 1143
反应条件
B-OMe-9-borabicyclo[3.3.1]nonane; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride in tetrahydrofuran
Heating;
参考文献
Fuerstner, Alois; Seidel, Guenter
Tetrahedron, 1995 , vol. 51, # 41 p. 11165 - 11176
反应条件
potassium fluoride; potassium iodide; palladium on activated charcoal in N,N-dimethyl-formamide
T=130°C; Sonogashira coupling; 48 h;
参考文献
Thathagar, Mehul B.; Rothenberg, Gadi
Organic and Biomolecular Chemistry, 2006 , vol. 4, # 1 p. 111 - 115
反应条件
2,2,6,6-tetramethylpiperidinyl-lithium in tetrahydrofuran; diethyl ether
T=-55°C; 14 h; Inert atmosphere;
参考文献
Truong, Thanh; Daugulis, Olafs
Organic Letters, 2011 , vol. 13, # 16 p. 4172 - 4175
反应条件
potassium acetate in 3,6,9,12,15,18,21,24,27-nonaoxanonacosane-1,29-diol
T=90°C; Sonogashira-Hagihara reaction; 14 h;
参考文献
Firouzabadi, Habib; Iranpoor, Nasser; Kazemi, Faezeh; Gholinejad, Mohammad
Journal of Molecular Catalysis A: Chemical, 2012 , vol. 357, p. 154 - 161
反应条件
diazabicycloundecene in N-methyl-acetamide
参考文献
Fuji Photo Film Co., Ltd.
Patent: US4772534 A1, 1988 ;
反应条件
dichloro bis(acetonitrile) palladium(II) in N,N-dimethyl-formamide
T=20°C; 0.166667 h;
参考文献
Bumagin, N. A.; Bumagina, I. G.; Beletskaya, I. P.
Doklady Chemistry, 1984 , vol. 274, p. 39 - 42
Doklady Akademii Nauk SSSR, 1984 , vol. 274, # 4 p. 818 - 822
