4-(2-苯基-1-乙炔)苯甲腈合成路线 （共 64 条）
反应条件
1: With FeH(CO)(NO)(PPh3)2; phenyl silane; triethylamine in tetrahydrofuran
T=40°C;
2: With tetrabutyl ammonium fluoride in tetrahydrofuran
T=0°C; 2 h; Inert atmosphere; optical yield given as percent dediastereoselective reaction;
参考文献
Belger, Christian; Plietker, Bernd
Chemical Communications, 2012 , vol. 48, # 44 p. 5419 - 5421
反应条件
palladium dichloride in chlorobenzene
Reflux;
参考文献
Xie, Hou-Zhi; Gao, Qi; Liang, Ying; Wang, Heng-Shan; Pan, Ying-Ming
Green Chemistry, 2014 , vol. 16, # 4 p. 2132 - 2135
反应条件
palladium dichloride in chlorobenzene
4 h; Reflux; Overall yield = 93 percent;
参考文献
Xie, Hou-Zhi; Gao, Qi; Liang, Ying; Wang, Heng-Shan; Pan, Ying-Ming
Green Chemistry, 2014 , vol. 16, # 4 p. 2132 - 2135
反应条件
1: sodium hydroxide; water / ethanol / 4 h / |Reflux
2: sulfuric acid / 80 °C
View Scheme
参考文献
Phetrak, Nared; Rukkijakan, Thanya; Sirijaraensre, Jakkapan; Prabpai, Samran; Kongsaeree, Palangpon; Klinchan, Chayada; Chuawong, Pitak
Journal of Organic Chemistry, 2013 , vol. 78, # 24 p. 12703 - 12709
