R-2-(4-氟苯基)四氢吡咯合成路线 （共 4 条）
反应条件
1: C40H38O2Rh2 / 1,4-dioxane / 6 h / 70 °C / Inert atmosphere; Molecular sieve 2: potassium carbonate / water; N,N-dimethyl-formamide / 2 h / 20 °C / Inert atmosphere 3: naphthalenyllithium / tetrahydrofuran / 0.25 h / -78 °C / Inert atmosphere View Scheme
参考文献
Journal of the American Chemical Society, , vol. 133, # 32 p. 12394 - 12397
反应条件
D-glucose; (S)-imine reductase from Streptomyces sp. GF3546; NADPH in aq. phosphate buffer; N,N-dimethyl-formamide T=30°C; pH=7; 18 h; Enzymatic reaction; Kinetics; enantioselective reaction;
参考文献
ChemCatChem, , vol. 5, # 12 p. 3505 - 3508
反应条件
1: C40H38O2Rh2 / 1,4-dioxane / 6 h / 70 °C / Inert atmosphere; Molecular sieve
2: potassium carbonate / water; N,N-dimethyl-formamide / 2 h / 20 °C / Inert atmosphere
3: naphthalenyllithium / tetrahydrofuran / 0.25 h / -78 °C / Inert atmosphere
View Scheme
参考文献
Cui, Zhe; Yu, Hong-Jie; Yang, Rui-Feng; Gao, Wen-Yun; Feng, Chen-Guo; Lin, Guo-Qiang
Journal of the American Chemical Society, 2011 , vol. 133, # 32 p. 12394 - 12397
反应条件
D-glucose; (S)-imine reductase from Streptomyces sp. GF3546; NADPH in aq. phosphate buffer; N,N-dimethyl-formamide
T=30°C; pH=7; 18 h; Enzymatic reaction; Kinetics; enantioselective reaction;
参考文献
Leipold, Friedemann; Hussain, Shahed; Ghislieri, Diego; Turner, Nicholas J.
ChemCatChem, 2013 , vol. 5, # 12 p. 3505 - 3508
