sodium hydroxide 6 h; Ambient temperature;

1: 60 percent / 50percent aq. NaOH, benzyltriethylammonium chloride / CH2Cl2; 1,2-dimethoxy-ethane / 1 h 2: 80 percent / NaOH / 2 h / 120 °C 3: BCl3 / CH2Cl2 / 17 h / -20 °C 4: conc. aq. ammonia / methanol / 17 h / Ambient temperature View Scheme

sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride in ethylene glycol dimethyl ether; dichloromethane 1 h;

1: 60 percent / 50percent aq. NaOH, benzyltriethylammonium chloride / CH2Cl2; 1,2-dimethoxy-ethane / 1 h 2: 80 percent / NaOH / 2 h / 120 °C View Scheme