DL-ALPHA-甲基色胺合成路线 （共 3 条）
反应条件
1: 56 percent / 2 N aq. H2SO4 / 0.5 h / 100 °C 2: 68 percent / Na2CO3 / acetone / 12 h / Heating 3: 55 percent / LiAlH4 / tetrahydrofuran; diethyl ether / 18 h / Heating View Scheme
参考文献
Pogosyan, S. A.; Matevosyan, L. A.; Melik-Ogandzhanyan, A. S.; Safrazbekyan, R. R.; Arzanunts, E. M.; et al.
Pharmaceutical Chemistry Journal, 1986 , vol. 20, # 10 p. 714 - 717
Khimiko-Farmatsevticheskii Zhurnal, 1986 , vol. 20, # 10 p. 1191 - 1195
反应条件
1: 90 percent / Et3N / CHCl3 / 20 h
2: 95 percent / LiAlH4 / tetrahydrofuran / 12 h / Heating
3: 95 percent / tert-butylamine / benzene / 15 h
View Scheme
参考文献
Dolicheva, I. N.; Smushkevich, Yu. I.; Suvorov, N. N.; Gridneva, L. I.; Gorkin, V. Z.; et al.
Pharmaceutical Chemistry Journal, 1983 , vol. 17, # 9 p. 603 - 607
Khimiko-Farmatsevticheskii Zhurnal, 1983 , vol. 17, # 9 p. 1033 - 1037
反应条件
triethylamine in chloroform
20 h;
参考文献
Dolicheva, I. N.; Smushkevich, Yu. I.; Suvorov, N. N.; Gridneva, L. I.; Gorkin, V. Z.; et al.
Pharmaceutical Chemistry Journal, 1983 , vol. 17, # 9 p. 603 - 607
Khimiko-Farmatsevticheskii Zhurnal, 1983 , vol. 17, # 9 p. 1033 - 1037
