2-羟基甲基-1,4-二氧杂烷合成路线 （共 14 条）
反应条件
phosphorus trichoride
参考文献
Tsivunin, V. S.; Zaripova, V. G.; Bikulova, V. Zh.; Zykova, V. V.; Kapustina, I. V.
Journal of Organic Chemistry USSR (English Translation), 1983 , vol. 19, # 3 p. 580
Zhurnal Organicheskoi Khimii, 1983 , vol. 19, # 3 p. 660 - 661
反应条件
phosphorus trichoride
参考文献
Tsivunin, V. S.; Zaripova, V. G.; Bikulova, V. Zh.; Zykova, V. V.
J. Gen. Chem. USSR (Engl. Transl.), 1983 , vol. 53, # 4 p. 938 - 939,826 - 827
反应条件
hydrogenchloride in methanol
T=20 - 40°C; 2 h;
参考文献
Eisai Co., Ltd.
Patent: US2007/10542 A1, 2007 ;
Location in patent: Page/Page column 80 ;
反应条件
lithium aluminium tetrahydride; aluminium trichloride in diethyl ether
Heating;
参考文献
Duclos, Richard I.; Makriyannis, Alexandros
Journal of Organic Chemistry, 1992 , vol. 57, # 23 p. 6156 - 6163
反应条件
sodium hydroxide in water
T=90°C; 2 h;
参考文献
Tsivunin, V. S.; Zaripova, V. G.; Bikulova, V. Zh.; Zykova, V. V.; Kapustina, I. V.
Journal of Organic Chemistry USSR (English Translation), 1983 , vol. 19, # 3 p. 580
Zhurnal Organicheskoi Khimii, 1983 , vol. 19, # 3 p. 660 - 661
反应条件
1: H2 / 20 percent Pd(OH)2 / C / methanol / 3 h / 2585.7 Torr
2: 26 percent / t-BuOK / 2-methyl-propan-2-ol / 1 h / rt to 65 deg C
3: 67 percent / LiAlH4, AlCl3 / diethyl ether / Heating
View Scheme
参考文献
Duclos, Richard I.; Makriyannis, Alexandros
Journal of Organic Chemistry, 1992 , vol. 57, # 23 p. 6156 - 6163
反应条件
1: 26 percent / t-BuOK / 2-methyl-propan-2-ol / 1 h / rt to 65 deg C
2: 67 percent / LiAlH4, AlCl3 / diethyl ether / Heating
View Scheme
参考文献
Duclos, Richard I.; Makriyannis, Alexandros
Journal of Organic Chemistry, 1992 , vol. 57, # 23 p. 6156 - 6163
反应条件
hydrogenchloride
2 h; Heating;
参考文献
Krasavtsev I. I.; Basalkevich E. D.; Lozinskii M. O.
Journal of Organic Chemistry USSR (English Translation), 1985 , vol. 21, p. 1632 - 1634
Zhurnal Organicheskoi Khimii, 1985 , vol. 21, # 8 p. 1787 - 1790
反应条件
1: 60 percent / NaOH
2: 36 percent / NaOH / H2O / 2 h / 90 °C
View Scheme
参考文献
Tsivunin, V. S.; Zaripova, V. G.; Bikulova, V. Zh.; Zykova, V. V.; Kapustina, I. V.
Journal of Organic Chemistry USSR (English Translation), 1983 , vol. 19, # 3 p. 580
Zhurnal Organicheskoi Khimii, 1983 , vol. 19, # 3 p. 660 - 661
反应条件
sulfuric acid
T=0°C;
参考文献
Pallavicini, Marco; Valoti, Ermanno; Villa, Luigi
Enantiomer, 2001 , vol. 6, # 5 p. 267 - 273
