2,5-二氟苯甲酸合成路线

参考文献

Journal of Medicinal Chemistry, , vol. 25, # 1 p. 84 - 86

参考文献

Vara Prasad; Boyer, Frederick E.; Chupak, Lou; Dermyer, Michael; Ding, Qizhu; Gavardinas; Hagen, Susan E.; Huband, Michael D.; Jiao, Wenhua; Kaneko, Takushi; Maiti, Samarendra N.; Melnick, Michael; Romero, Karina; Patterson; Wu, Xiujuan
Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 20 p. 5392 - 5397

2991-28-82,5-二氟苯甲酸

741721-49-3+

741721-50-6

参考文献

WARNER-LAMBERT COMPANY LLC
Patent: WO2004/69832 A2, 2004 ;
Location in patent: Page 134 ;

2991-28-82,5-二氟苯甲酸

741721-51-71-溴-2,5-二氟-3-硝基苯

参考文献

Vara Prasad; Boyer, Frederick E.; Chupak, Lou; Dermyer, Michael; Ding, Qizhu; Gavardinas; Hagen, Susan E.; Huband, Michael D.; Jiao, Wenhua; Kaneko, Takushi; Maiti, Samarendra N.; Melnick, Michael; Romero, Karina; Patterson; Wu, Xiujuan
Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 20 p. 5392 - 5397

16867-03-12-氨基-3-羟基吡啶+

2991-28-82,5-二氟苯甲酸

52333-66-1

参考文献

Clark,R.L. et al.
Journal of Medicinal Chemistry, 1978 , vol. 21, p. 1158 - 1162

2991-28-82,5-二氟苯甲酸

455-38-9间氟苯甲酸+

65-85-0苯甲酸

参考文献

Konovalov, Valery V.; Laev, Sergey S.; Beregovaya, Irina V.; Shchegoleva, Lyudmila N.; Shteingarts, Vitalij D.; Tsvetkov, Yuri D.; Bilkis, Itzhak
Journal of Physical Chemistry A, 2000 , vol. 104, # 2 p. 352 - 361