N-乙基-N-[(十七氟辛基)磺酰基]甘氨酸合成路线 （共 4 条）
反应条件
sodium hydroxide in 1,4-dioxane
T=65°C; 2 h;
参考文献
Lehmler, Hans-Joachim; Rama Rao; Nauduri, Dhananjaya; Vargo, John D.; Parkin, Sean
Journal of Fluorine Chemistry, 2007 , vol. 128, # 6 p. 595 - 607
反应条件
1.1: triethylamine / diethyl ether / 17 h / 0 - 20 °C
1.2: 56 percent / aq. NaHCO3 / diethyl ether / 3 h / Heating
2.1: 90 percent / potassium carbonate; sodium iodide / acetone / 3 h / Heating
3.1: 40 percent / aq. NaOH / dioxane / 2 h / 65 °C
View Scheme
参考文献
Lehmler, Hans-Joachim; Rama Rao; Nauduri, Dhananjaya; Vargo, John D.; Parkin, Sean
Journal of Fluorine Chemistry, 2007 , vol. 128, # 6 p. 595 - 607
反应条件
1: 90 percent / potassium carbonate; sodium iodide / acetone / 3 h / Heating
2: 40 percent / aq. NaOH / dioxane / 2 h / 65 °C
View Scheme
参考文献
Lehmler, Hans-Joachim; Rama Rao; Nauduri, Dhananjaya; Vargo, John D.; Parkin, Sean
Journal of Fluorine Chemistry, 2007 , vol. 128, # 6 p. 595 - 607
反应条件
di-isopropyl ether
Erwaermen des Reaktionsprodukts mit Chloressigsaeure-aethylester, NaOH, Na2CO3 und wss. Aceton;
参考文献
Minnesota Mining and Mfg. Co.
Patent: US2809990 , 1955 ;
