2-氨基-5,6-二甲基苯并噻唑合成路线 （共 11 条）
参考文献
Zhurnal Obshchei Khimii, , vol. 22, p. 516,518; engl. Ausg. S. 581, 584
反应条件
ammonium hydroxide; bromine; acetic acid 1.) room temp. 2.) room temp.; Yield given. Multistep reaction;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 39, # 11 p. 2888 - 2895
反应条件
1: H2O / zuletzt ohne Loesungsmittel 2: bromine; CHCl3 View Scheme
参考文献
Zhurnal Obshchei Khimii, , vol. 22, p. 516,518; engl. Ausg. S. 581, 584
反应条件
1: chlorobenzene; ammonium-thiocyanate 2: bromine; S2cl2; chlorobenzene View Scheme
参考文献
Journal of the Chemical Society, , p. 2217,2223
参考文献
Costakis,E. et al.
Canadian Journal of Chemistry, 1969 , vol. 47, p. 4483 - 4488
反应条件
1: aqueous KOH / 210 °C / und anschliessend mit Acetanhydrid und Essigsaeure 2: zinc-powder; acetic acid; acetic acid anhydride View Scheme
参考文献
Barany; Pianka
Journal of the Chemical Society, 1953 , p. 2217,2223
参考文献
Lewkoew et al.
Zhurnal Obshchei Khimii, 1952 , vol. 22, p. 516,518; engl. Ausg. S. 581, 584
反应条件
210 deg C, 1.5 h; ethanol, reflux, 5 min.;
参考文献
Daidone; Raffa; Plescia; Matera; Caruso; Leone; Amico-Roxas
Farmaco, 1989 , vol. 44, # 5 p. 465 - 473
反应条件
triethylamine in tetrahydrofuran
4 h; Ambient temperature;
参考文献
Glennon; Gaines; Rogers
Journal of Medicinal Chemistry, 1981 , vol. 24, # 6 p. 766 - 769
参考文献
Abignente; Arena; De Caprariis; Parente
Farmaco, Edizione Scientifica, 1976 , vol. 31, # 12 p. 880 - 887
