四氢吡喃酮合成路线

参考文献

ZENOBIA THERAPEUTICS, INC.; BOUNAUD, Pierre-Yves; NIENABER, Vicki; STEENSMA, Ruo, W.; LOWE, John, A., III
Patent: WO2012/178015 A2, 2012 ;
Location in patent: Page/Page column 119 ;
WO 2012/178015 A2

29943-42-8四氢吡喃酮+

177703-80-9

4295-99-24-氰基四氢吡喃

参考文献

Bristol-Myers Squibb Company
Patent: US2008/4265 A1, 2008 ;
Location in patent: Page/Page column 18 ;

29943-42-8四氢吡喃酮

4295-99-24-氰基四氢吡喃

参考文献

BRISTOL-MYERS SQUIBB COMPANY
Patent: WO2007/58646 A1, 2007 ;
Location in patent: Page/Page column 39-40 ;

29943-42-8四氢吡喃酮+

243661-09-8

4295-99-24-氰基四氢吡喃

参考文献

Bristol-Myers Squibb Company
Patent: US2008/306051 A1, 2008 ;
Location in patent: Page/Page column 15 ;

29943-42-8四氢吡喃酮

4295-99-24-氰基四氢吡喃

参考文献

Chen, Li; Chen, Shaoqing; Michoud, Christophe
Patent: US2006/63804 A1, 2006 ;
Location in patent: Page/Page column 13 ;
US 20060063804 A1

29943-42-8四氢吡喃酮+

2942-58-7氰基磷酸二乙酯

4295-99-24-氰基四氢吡喃

参考文献

Vertex Pharmaceuticals, Incorporated
Patent: US6372778 B1, 2002 ;
Location in patent: Example 80 ;
US 6372778 B1

29943-42-8四氢吡喃酮

4677-18-32-四氢吡喃-4-乙醇

参考文献

Berthel, Steven Joseph; Chen, Li; Corbett, Wendy Lea; Feng, LiChun; Haynes, Nancy-Ellen; Kester, Robert Francis; So, Sung-Sau; Tilley, Jefferson Wright
Patent: US2011/144105 A1, 2011 ;

29943-42-8四氢吡喃酮

33024-60-14-氨基四氢吡喃盐酸盐

参考文献

Takeda Pharmaceutical Company Limited
Patent: EP1535922 A1, 2005 ;
Location in patent: Page/Page column 40 ;

29943-42-8四氢吡喃酮

40191-32-04-氢吡喃-4-甲酰氯

参考文献

Morris, David J.; Hayes, Aidan M.; Wills, Martin
Journal of Organic Chemistry, 2006 , vol. 71, # 18 p. 7035 - 7044

29943-42-8四氢吡喃酮

398137-19-41-(四氢-2H-吡喃-4-基)哌嗪

参考文献

Zaragoza, Florencio; Stephensen, Henrik; Knudsen, Sanne M.; Pridal, Lone; Wulff, Birgitte S.; Rimvall, Karin
Journal of Medicinal Chemistry, 2004 , vol. 47, # 11 p. 2833 - 2838