2-(3-甲氧基苯基)-1-苯乙酮合成路线 （共 14 条）
反应条件
nickel in ethylene glycol dimethyl ether
T=85°C; 0.25 h;
参考文献
Inaba, Shin-ichi; Rieke, Reuben D.
Journal of Organic Chemistry, 1985 , vol. 50, # 9 p. 1373 - 1381
反应条件
FibreCatTM 1000-D7; sodium t-butanolate in tetrahydrofuran
T=85°C; 6 h;
参考文献
Churruca, Fatima; SanMartin, Raul; Carril, Monica; Tellitu, Imanol; Dominguez, Esther
Tetrahedron, 2004 , vol. 60, # 10 p. 2393 - 2408
反应条件
hydrogenchloride; magnesium in methanol; benzonitrile
参考文献
Pennwalt Corporation
Patent: US4782058 A1, 1988 ;
反应条件
C41H46Cl2FeN4Pd; potassium tert-butylate in 1,4-dioxane
T=100°C; 3 h; Inert atmosphere;
参考文献
Xu, Chen; Li, Hong-Mei; Wang, Zhi-Qiang; Fu, Wei-Jun; Zhang, Yu-Qing; Ji, Bao-Ming
Australian Journal of Chemistry, 2012 , vol. 65, # 4 p. 366 - 370
反应条件
in tetrahydrofuran
T=0 - 20°C; Inert atmosphere;
参考文献
MERCK SHARP and DOHME CORP.; DWYER, Michael P; KEERTIKAR, Kartik M; COBURN, Craig A; WU, Hao; HU, Bin; ZHONG, Bin; ZHANG, Chengren; DAN, Zhigang; TONG, Ling; YU, Wensheng
Patent: WO2012/41227 A1, 2012 ;
Location in patent: Page/Page column 117 ;
WO 2012/041227 A1
反应条件
1: m-methoxybenzyl diethyl phosphate With manganese in tetrahydrofuran
T=20°C; 8 h;
2: benzoyl chloride in tetrahydrofuran
T=20°C; 1 h;
参考文献
Suh, YoungSung; Lee, Jun-Sik; Kim, Seoung-Hoi; Rieke, Reuben D.
Journal of Organometallic Chemistry, 2003 , vol. 684, # 1-2 p. 20 - 36
反应条件
palladium(II) dichloride bis[bis(diphenylphosphine)ferrocene] dichloromethane; 1,8-diazabicyclo[5.4.0]undec-7-ene in N,N-dimethyl-formamide
T=100°C; Stille coupling; 16 h;
参考文献
Saevmarker, Jonas; Lindh, Jonas; Nilsson, Peter
Tetrahedron Letters, 2010 , vol. 51, # 52 p. 6886 - 6889
反应条件
palladium diacetate; 1,4-di(diphenylphosphino)-butane; zinc in 1,4-dioxane
T=100°C; Negishi coupling reaction; P=7500.75 Torr; 16 h; Inert atmosphereAutoclave;
参考文献
Wu, Xiao-Feng; Schranck, Johannes; Neumann, Helfried; Beller, Matthias
Chemistry - An Asian Journal, 2012 , vol. 7, # 1 p. 40 - 44
反应条件
in tetrahydrofuran
T=-78 - 20°C; 1 h;
参考文献
Schneider, Martin R.; Angerer, Erwin von; Schoenenberger, Helmut; Michel, Ralf Th.; Fortmeyer, H. P.
Journal of Medicinal Chemistry, 1982 , vol. 25, # 9 p. 1070 - 1077
反应条件
FibreCatTM 1001; sodium t-butanolate in tetrahydrofuran
T=85°C; 6 h; Title compound not separated from byproducts.;
参考文献
Churruca, Fatima; SanMartin, Raul; Carril, Monica; Tellitu, Imanol; Dominguez, Esther
Tetrahedron, 2004 , vol. 60, # 10 p. 2393 - 2408
