2-(3-甲氧基苯基)-1-苯乙酮合成路线 （共 14 条）
反应条件
1: (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / dichloromethane / 0 - 20 °C
2: tetrahydrofuran / 0 - 20 °C / Inert atmosphere
View Scheme
参考文献
MERCK SHARP and DOHME CORP.; DWYER, Michael P; KEERTIKAR, Kartik M; COBURN, Craig A; WU, Hao; HU, Bin; ZHONG, Bin; ZHANG, Chengren; DAN, Zhigang; TONG, Ling; YU, Wensheng
Patent: WO2012/41227 A1, 2012 ;
WO 2012/041227 A1
参考文献
Aguirre, J. M .; Alesso, E. N.; Ibanez, A. F.; Tombari, D. G.; Moltrasio Iglesias G. Y.
Journal of Heterocyclic Chemistry, 1989 , vol. 26, p. 25 - 27
反应条件
FibreCatTM 1026; caesium carbonate in N,N-dimethyl-formamide
T=153°C; Product distribution; Further Variations:ReagentsReaction partners;
参考文献
Churruca, Fatima; SanMartin, Raul; Tellitu, Imanol; Dominguez, Esther
Tetrahedron Letters, 2003 , vol. 44, # 31 p. 5925 - 5929
反应条件
palladium (II) trifluoroacetate; caesium carbonate in N,N-dimethyl-formamide
T=150°C; 1.5 h; Product distribution; Further Variations:Reagents;
参考文献
Churruca, Fatima; SanMartin, Raul; Carril, Monica; Tellitu, Imanol; Dominguez, Esther
Tetrahedron, 2004 , vol. 60, # 10 p. 2393 - 2408
