5-氟-1H-苯并咪唑-2-甲腈合成路线 （共 3 条）
反应条件
ammonium hydroxide in ethanol; water T=-5 - 20°C;
参考文献
Lane, Charlotte A.L.; Hay, Duncan; Mowbray, Charles E.; Paradowski, Michael; Selby, Matthew D.; Swain, Nigel A.; Williams, David H.
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 2 p. 1156 - 1159
反应条件
1: acetic acid / 20 °C 2: ammonium hydroxide / ethanol; water / -5 - 20 °C View Scheme
参考文献
Lane, Charlotte A.L.; Hay, Duncan; Mowbray, Charles E.; Paradowski, Michael; Selby, Matthew D.; Swain, Nigel A.; Williams, David H.
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 2 p. 1156 - 1159
反应条件
1: hydrogenchloride; iron / ethanol; water / Reflux 2: acetic acid / 20 °C 3: ammonium hydroxide / ethanol; water / -5 - 20 °C View Scheme
参考文献
Lane, Charlotte A.L.; Hay, Duncan; Mowbray, Charles E.; Paradowski, Michael; Selby, Matthew D.; Swain, Nigel A.; Williams, David H.
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 2 p. 1156 - 1159
