3,5-二碘-L-酪氨酸合成路线 （共 23 条）
反应条件
in N,N-dimethyl-formamide T=24°C; 16 h; 0.2 M borate buffer, pH 8.0 (add. of 0.1 M NaOH);
参考文献
Salamonczyk, Grzegorz M.; Oza, Vibha B.; Sih, Charles J.
Tetrahedron Letters, 1997 , vol. 38, # 40 p. 6965 - 6968
反应条件
1: 48 percent / conc. HCl / 1,2-dimethoxy-ethane / 18.5 h / 72 °C 2: 73 percent / hydrogen, Et3N / 10 percent Pd-C / ethanol; H2O / 3 h / 25 °C / 2068.6 Torr View Scheme
参考文献
BRISTOL-MYERS SQUIBB COMPANY; BORZILLERI, Robert M.; PEREZ, Heidi L.; STANG, Erik M.; KIM, Kyoung S.
Patent: WO2013/192286 A1, 2013 ;
反应条件
potassium carbonate in toluene T=20°C; 20 h;
参考文献
Skaff, Ojia; Jolliffe, Katrina A.; Hutton, Craig A.
Journal of Organic Chemistry, 2005 , vol. 70, # 18 p. 7353 - 7363
