2,3-二溴-N-甲基马来酰亚胺合成路线 （共 24 条）
反应条件
nitric acid in acetic acid T=25°C; 2 h; Inert atmosphere;
参考文献
European Journal of Inorganic Chemistry, , # 7 p. 1114 - 1121
反应条件
1: With N-bromosuccinmide in tetrahydrofuran 2: With nitric acid
参考文献
Wang, Ke; Liu, Zhan-Zhu
Journal of Asian Natural Products Research, 2014 , vol. 16, # 3 p. 296 - 303
反应条件
bromine in acetic acid 1 h; Ambient temperature;
参考文献
Journal of Organic Chemistry, , vol. 49, # 21 p. 4065 - 4067
参考文献
Choi, Dong-Sook; Huang, Shenlin; Huang, Mingsheng; Barnard, Thomas S.; Adams, Richard D.; Seminario, Jorge M.; Tour, James M.
Journal of Organic Chemistry, 1998 , vol. 63, # 8 p. 2646 - 2655
参考文献
Australian Journal of Chemistry, , vol. 56, # 4 p. 263 - 267
参考文献
Chemische Berichte, , vol. 21, p. 2871
反应条件
2.) 580 deg C, 0.01 torr; Multistep reaction;
参考文献
Tetrahedron Letters, , vol. 28, # 51 p. 6503 - 6506
反应条件
1: 90 percent / ceric ammonium nitrate / aq. ethanol / 0.17 h / 0 °C 2: 45 percent / granulated zinc/silver couple / tetrahydrofuran / 1 h / Heating View Scheme
参考文献
Australian Journal of Chemistry, , vol. 44, # 9 p. 1275 - 1292
反应条件
1: With ethyl bromide; iodine; magnesium in tetrahydrofuran T=30 - 40°C; 1.5 h; 2: iodine in tetrahydrofuran; toluene T=30 - 40°C; 1 h; 3: 3,4-dibromo-N-methylmaleimide in tetrahydrofuran; toluene T=110°C; 1 h;
参考文献
SUVEN life sciences limited
Patent: WO2004/83202 A1, 2004 ;
Location in patent: Page 17-18 ;
反应条件
1: indole With lithium hexamethyldisilazane in hexane; toluene T=-78°C; 0.75 h; 2: 3,4-dibromo-N-methylmaleimide in hexane; toluene 12 h; Heating;
参考文献
Synthesis, , # 12 art. no. T00305SS, p. 1959 - 1966
