2,3-二溴-N-甲基马来酰亚胺合成路线 （共 24 条）
反应条件
N,N,N',N',N'',N''-hexamethylphosphoric triamide in benzene T=25°C;
参考文献
Angewandte Chemie, , vol. 92, # 6 p. 463 - 464
参考文献
Journal of Antibiotics, , vol. 55, # 8 p. 768 - 773
反应条件
ethylmagnesium bromide in diethyl ether; benzene examination of further solvents, temperature, reaction time and the quantity of indole; Product distribution;
参考文献
Tetrahedron, , vol. 44, p. 2887
反应条件
1: 1) CH2Cl2, AlCl3, 0 deg C; 2) DMSO 2: 93 percent / CH2Cl2 / 15 h / Heating 3: Zn/Ag / tetrahydrofuran / 0.05 h / Heating 4: 93 percent / Zn/Ag / tetrahydrofuran / 4 h / Heating 5: pyrolysis View Scheme
参考文献
Warrener; Bina; Butler; Pitt; Russell
Tetrahedron Letters, 1990 , vol. 31, # 48 p. 7073 - 7076
反应条件
lithium chloride; bis-triphenylphosphine-palladium(II) chloride in toluene 15 h; Heating;
参考文献
Bioorganic and Medicinal Chemistry, , vol. 16, # 9 p. 5303 - 5321
反应条件
2.) 580 deg C, 0.01 torr; Multistep reaction;
参考文献
Tetrahedron Letters, , vol. 28, # 51 p. 6503 - 6506
反应条件
1: With ethyl bromide; iodine; magnesium in tetrahydrofuran
T=30 - 40°C; 1.5 h;
2: iodine in tetrahydrofuran; toluene
T=30 - 40°C; 1 h;
3: 3,4-dibromo-N-methylmaleimide in tetrahydrofuran; toluene
T=110°C; 1 - 2 h;
参考文献
SUVEN life sciences limited
Patent: WO2004/83202 A1, 2004 ;
Location in patent: Page 16 ;
反应条件
acetone
15 h; Irradiation;
参考文献
Szilagyi; Wamhoff
Angewandte Chemie, 1980 , vol. 92, # 12 p. 1066 - 1067
反应条件
benzophenone in 1,4-dioxane
24 h; Irradiation;
参考文献
Szilagyi; Wamhoff
Angewandte Chemie, 1980 , vol. 92, # 12 p. 1066 - 1067
反应条件
acetone
15 h; Irradiationeffect of use var. solvents, times and sensitizer (benzophenone); Product distribution;
参考文献
Szilagyi; Wamhoff
Angewandte Chemie, 1980 , vol. 92, # 12 p. 1066 - 1067
