2-(乙酰氨基)-2-脱氧-BETA-D-半乳糖 1,3,4,6-四乙酸酯合成路线 （共 60 条）
反应条件
hydrogenchloride; methanol als Hydrochlorid;
参考文献
Foster et al.
Journal of the Chemical Society, 1957 , p. 81,85
反应条件
1: 1. BF3*Et2O 2. trimethylsilyl trifluoromethanesulfonate / 1. CH2Cl2, room temperature 2. 1,2-dichloroethane 2: NaOCH3 / methanol 3: 3 g / p-TosOH / acetone / 1 h / Heating 4: barium hydroxide, barium oxide / dimethylformamide 5: 1.89 g / amberlyst 15 (H+) / methanol; H2O / 6 h / Ambient temperature 6: 69 percent / dibutyltin oxide, tetrabutylammonium iodide / benzene / 24 h / Heating View Scheme
参考文献
Carbohydrate Research, , vol. 202, p. 239 - 255
反应条件
4A MS in methanol T=20°C; 48 h;
参考文献
Kartha, K.P. Ravindranathan; Mukhopadhyay, Balaram; Field, Robert A.
Carbohydrate Research, 2004 , vol. 339, # 3 p. 729 - 732
反应条件
1: toluene-4-sulfonic acid 2: sodium methylate; methanol View Scheme
参考文献
Fujise; Yokoyama
Nippon Kagaku Zasshi, 1951 , vol. 72, p. 728
Chem.Abstr., 1952 , p. 11 116
反应条件
toluene-4-sulfonic acid
参考文献
Fujise; Yokoyama
Nippon Kagaku Zasshi, 1951 , vol. 72, p. 728
Chem.Abstr., 1952 , p. 11 116
反应条件
1: acetic acid anhydride; hydrogen chloride 2: acetone; aq. NaOH solution View Scheme
参考文献
Leaback; Walker
Journal of the Chemical Society, 1957 , p. 4754,4757
反应条件
1: TfOH 2: trimethylsilyl trifluoromethanesulfonate / dichloromethane / 72 h / 20 °C View Scheme
参考文献
Krenek, Karel; Simon, Petr; Weignerova, Lenka; Fliedrova, Barbora; Kuzma, Marek; Kren, Vladimir
Beilstein Journal of Organic Chemistry, 2012 , vol. 8, p. 428 - 432
反应条件
1: toluene-4-sulfonic acid 2: sodium methylate; methanol; chloroform View Scheme
参考文献
Leaback; Walker
Journal of the Chemical Society, 1957 , p. 4754,4757
反应条件
camphor-10-sulfonic acid in benzene Heatingazeotropic removal of acetic acid;
参考文献
Sowell, C. Gregory; Livesay, Mark T.; Johnson, David A.
Tetrahedron Letters, 1996 , vol. 37, # 5 p. 609 - 610
反应条件
1: 71 percent / aluminum iodide, Ca, NaI / acetonitrile / 5 h / 45 °C 2: 51 percent / aluminum iodide / acetonitrile / 40 °C View Scheme
参考文献
Pertel', S. S.; Chirva, V. Ya.
Russian Journal of Organic Chemistry, 1993 , vol. 29, # 5.2 p. 867 - 869
Zhurnal Organicheskoi Khimii, 1993 , vol. 29, # 5 p. 1051 - 1053
