3,4,5-三氯苯-1,2-二胺合成路线 （共 6 条）
反应条件
hydrogenchloride; iron in ethanol Reduction; 3.5 h; Heating;
参考文献
Gudmundsson, Kristjan S.; Tidwell, Jeffrey; Lippa, Nicole; Koszalka, George W.; van Draanen, Nanine; Ptak, Roger G.; Drach, John C.; Townsend, Leroy B.
Journal of Medicinal Chemistry, 2000 , vol. 43, # 12 p. 2464 - 2472
反应条件
sodium hydrogencarbonate in ethanol
参考文献
State of Oregon, Acting by and through the Oregon State Board of Higher Education, Acting for and on Behalf of the Oregon Health Sciences University and the University of Oregon; Acea Pharmaceuticals, Inc.; The Regents of the University of California
Patent: US5597922 A1, 1997 ;
US 5597922 A
反应条件
hydrogenchloride; sodium carbonate in ethanol
参考文献
Glaxo Wellcome Inc.
Patent: US6204249 B1, 2001 ;
反应条件
1: 98 percent / N-chlorosuccinimide / dimethylformamide / 1 h / 100 °C 2: 72 percent / iron powder; concd HCl / ethanol / 3.5 h / Heating View Scheme
参考文献
Gudmundsson, Kristjan S.; Tidwell, Jeffrey; Lippa, Nicole; Koszalka, George W.; van Draanen, Nanine; Ptak, Roger G.; Drach, John C.; Townsend, Leroy B.
Journal of Medicinal Chemistry, 2000 , vol. 43, # 12 p. 2464 - 2472
反应条件
hydrogenchloride; tin
参考文献
Merck and Co. Inc.
Patent: US2876230 , 1957 ;
Full Text Show Details
Merck and Co. Inc.
Patent: DE1011426 , 1955 ;
参考文献
Merck and Co. Inc.
Patent: US2876230 , 1957 ;
Full Text Show Details
Merck and Co. Inc.
Patent: DE1011426 , 1955 ;
