(1-烯丙基-1H-苯并咪唑-2-基)甲醇合成路线 (共 6 条)
反应条件
1: (1H-benzoimidazol-2-yl)-methanol With triethylamine in tetrahydrofuran 1 h; Heating; 2: allyl bromide in tetrahydrofuran 3 h; Heating;
参考文献
O'Shaughnessy, John; Aldabbagh, Fawaz
Synthesis, 2005 , # 7 art. no. P14504SS, p. 1069 - 1076
反应条件
sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride in acetone T=20°C; 2 h;
参考文献
Popov
Chemistry of Heterocyclic Compounds, 1996 , vol. 32, # 6 p. 672 - 681
反应条件
1.1: 57 percent / aq. HCl / Heating 2.1: Et3N / tetrahydrofuran / 1 h / Heating 2.2: 41 percent / tetrahydrofuran / 3 h / Heating View Scheme
参考文献
O'Shaughnessy, John; Aldabbagh, Fawaz
Synthesis, 2005 , # 7 art. no. P14504SS, p. 1069 - 1076
反应条件
1: 91 percent / triethylbenzylammonium hydroxide / dimethylformamide / 5 h / Heating 2: 82 percent / Heating 3: 5 percent / NaHCO3 / Heating View Scheme
参考文献
Popov
Chemistry of Heterocyclic Compounds, 1996 , vol. 32, # 6 p. 672 - 681
反应条件
1: 82 percent / Heating 2: 5 percent / NaHCO3 / Heating View Scheme
参考文献
Popov
Chemistry of Heterocyclic Compounds, 1996 , vol. 32, # 6 p. 672 - 681
反应条件
manganese(IV) oxide in dichloromethane 0.5 h; Heating;
参考文献
O'Shaughnessy, John; Aldabbagh, Fawaz
Synthesis, 2005 , # 7 art. no. P14504SS, p. 1069 - 1076