反应条件
1: (R)-DTBM-Segphos; [(Cu(OTf))2(μ-toluene)]; potassium methanolate / dichloromethane; 1,4-dioxane / 48 h / 15 °C / |Sealed tube; |Inert atmosphere 2: toluene-4-sulfonic acid hydrazide; triethylamine / 1,4-dioxane / 1 h / 120 °C / |Inert atmosphere 3: tetrafluoroboric acid diethyl ether complex / dichloromethane / 1 h / 20 °C / |Inert atmosphere 4: dihydrogen peroxide; potassium hydrogencarbonate; potassium fluoride / tetrahydrofuran; methanol / 6 h / 40 °C / |Inert atmosphere View Scheme
参考文献
Shido, Yoshinori; Yoshida, Mika; Tanabe, Masahito; Ohmiya, Hirohisa; Sawamura, Masaya
Journal of the American Chemical Society, 2012 , vol. 134, # 45 p. 18573 - 18576
