6-硝基-4-氧代-4H-1-苯并吡喃-2-羧酸乙酯合成路线 （共 4 条）
反应条件
sulfuric acid; potassium nitrate in water T=-10 - 20°C; 5 - 7 h;
参考文献
Kanter, James; Mullins, John J.G.; Pandey, Anjali; Scarborough, Robert
Patent: US2003/233002 A1, 2003 ;
Location in patent: Page 16 ;
反应条件
sodium ethanolate in ethanol; hexane; water; toluene
参考文献
Kanter, James; Mullins, John J.G.; Pandey, Anjali; Scarborough, Robert
Patent: US2003/233002 A1, 2003 ;
Location in patent: Page 15 ;
反应条件
1: sodium / ethanol / 1 h / |Reflux 2: sulfuric acid; nitric acid / water / 2 h / 20 °C / |Cooling with ice View Scheme
参考文献
Velema, Willem A.; Van Der Toorn, Marco; Szymanski, Wiktor; Feringa, Ben L.
Journal of Medicinal Chemistry, 2013 , vol. 56, # 11 p. 4456 - 4464
反应条件
palladium 10 on activated carbon; hydrogen in benzene T=20°C;
参考文献
Velema, Willem A.; Van Der Toorn, Marco; Szymanski, Wiktor; Feringa, Ben L.
Journal of Medicinal Chemistry, 2013 , vol. 56, # 11 p. 4456 - 4464
