(2-硝基苯基)乙酸甲酯合成路线 (共 35 条)
反应条件
sulfuric acid Esterification; 4 h; Heating;
参考文献
Liu, Bin; Hu, Longqin
Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 18 p. 3889 - 3899
反应条件
sulfuric acid in methanol; water
参考文献
Microcide Pharmaceuticals, Inc.; DAIICHI PHARMACEUTICAL CO., LTD.
Patent: EP1227084 A1, 2002 ;
反应条件
sulfuric acid; sodium hydrogencarbonate in methanol; chloroform
参考文献
DAIICHI PHARMACEUTICAL CO., LTD.
Patent: EP1346982 A1, 2003 ;
反应条件
N-ethyl-N,N-diisopropylamine; C52H46O2P2Pd2; triphenylphosphine T=60°C; 2 h; Conversion of starting material;
参考文献
HERIOT-WATT UNIVERSITY
Patent: WO2006/10885 A1, 2006 ;
Location in patent: Page/Page column 32 ;
反应条件
sulfuric acid; nitric acid 1 h; Ambient temperature;
参考文献
Bulletin of the Chemical Society of Japan, , vol. 68, # 4 p. 1155 - 1161
反应条件
potassium carbonate in water T=60°C;
参考文献
Selvakumar; Azhagan, A.Malar; Srinivas; Krishna, G.Gopi
Tetrahedron Letters, 2002 , vol. 43, # 50 p. 9175 - 9178
反应条件
sulfuric acid in methanol; dichloromethane
反应条件
sodium hydrogencarbonate in N,N-dimethyl-formamide Methylation; 8 h;
参考文献
Salerno; Magde; Patron
Journal of Organic Chemistry, 2000 , vol. 65, # 13 p. 3971 - 3981
反应条件
sulfuric acid; iodine in dimethyl sulfoxide T=60°C; 0.5 h; Acidic conditions;
参考文献
Nawghare, Beena R.; Lokhande, Pradeep D.
Synthetic Communications, 2013 , vol. 43, # 14 p. 1955 - 1963
反应条件
tris(dimethylamino)-sulphonium difluorotrimethylsilicate; bromine 1)THF, acetonitrile, -40 deg C, 30-60 min 2)-78 deg C; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Journal of Organic Chemistry, , vol. 49, # 23 p. 4571 - 4572