4,4’,4’-三甲氧基苯基甲醇合成路线 （共 42 条）
反应条件
1: 1-bromo-4-methoxy-benzene With magnesium in tetrahydrofuran 1 h; Inert atmosphereReflux; 2: carbonic acid dimethyl ester in tetrahydrofuran 4 h; Inert atmosphereReflux; 3: With water in tetrahydrofuran T=20°C; Inert atmosphere;
参考文献
Guieu, Samuel; Rocha, Joao; Silva, Artur M.S.
Tetrahedron Letters, 2013 , vol. 54, # 22 p. 2870 - 2873
反应条件
potassium hydroxide; 18-crown-6 ether; oxygen in ethylene glycol dimethyl ether T=20°C; 15 h;
参考文献
Artamkina, G. A.; Grinfel'd, A. A.; Beletskaya, I. P.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1983 , vol. 32, # 2 p. 345 - 352
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1983 , # 2 p. 383 - 391
反应条件
1: 1-bromo-4-methoxy-benzene With magnesium in tetrahydrofuran Reflux; 2: methyl 4-(N-tert-butoxycarbonyl-(5S)-methyl-(2S)-pyrrolidinylmethoxy)benzoate in tetrahydrofuran T=20°C; Reflux;
参考文献
Horn, Markus; Mayr, Herbert
Chemistry - A European Journal, 2010 , vol. 16, # 25 p. 7469 - 7477
反应条件
water in sulfuric acid; acetic acid Equilibrium constant;
参考文献
Collection of Czechoslovak Chemical Communications, , vol. 37, p. 585 - 591
反应条件
bis-(3,5-dinitro-benzoyl)-peroxide in 1,2-dichloro-ethane T=86°C; 3 h;
参考文献
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), , # 9 p. 1301 - 1310
反应条件
silver hexafluoroantimonate; An3COAn; water in 1,2-dichloro-ethane 0.25 h; Heating;
参考文献
Tetrahedron Letters, , vol. 32, # 27 p. 3187 - 3190
反应条件
boron trifluoride diethyl etherate in 1,2-dichloro-ethane T=50°C; 24 h; in a sealed tube;
参考文献
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), , p. 1987 - 1996
反应条件
bis-(3,5-dinitro-benzoyl)-peroxide in 1,2-dichloro-ethane T=75°C; 2 h;
参考文献
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), , # 9 p. 1301 - 1310
反应条件
trifluoroacetic acid; dibenzoyl peroxide in 1,2-dichloro-ethane T=25°C; 24 h; in a sealed tube;
参考文献
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), , p. 1987 - 1996
反应条件
2,3-benzodioxin-1,4-dione; trifluorormethanesulfonic acid in 1,2-dichloro-ethane T=25°C; 24 h; in a sealed tube; Further byproducts given;
参考文献
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), , p. 1987 - 1996
