7-羟基-4-氧代苯并吡喃-2-羧酸合成路线 （共 10 条）
反应条件
1: With sodium carbonate in ethanol; water T=80°C; 3 h; Heating / reflux; 2: With hydrogenchloride in ethanol; water
参考文献
MERCK PATENT GMBH
Patent: WO2005/97772 A1, 2005 ;
Location in patent: Page/Page column 68 ;
反应条件
sulfuric acid 2 h; Heating;
参考文献
Ellis, Gwynn P.; Hudson, Henrietta V.
Journal of Chemical Research, Miniprint, 1985 , # 12 p. 3830 - 3860
反应条件
hydrogen bromide; acetic acid
参考文献
Naylor et al.
Journal of the Chemical Society, 1958 , p. 1190,1192
反应条件
1: acetic acid; concentrated aqueous hydrochloric acid 2: acetic acid; aqueous hydrobromic acid View Scheme
参考文献
Naylor et al.
Journal of the Chemical Society, 1958 , p. 1190,1192
反应条件
1: sodium ethylate 2: acetic acid; concentrated aqueous hydrochloric acid 3: acetic acid; aqueous hydrobromic acid View Scheme
参考文献
Jacobson et al.
Journal of Organic Chemistry, 1953 , vol. 18, p. 1117,1121
反应条件
1: 2) hydrated FeCl3 / 1) HMPA, 120 deg C, 3 h, 2) aq.HCl, 70 deg C, 20 min 2: 76 percent / 70percent aq.H2SO4 / 2 h / Heating View Scheme
参考文献
Ellis, Gwynn P.; Hudson, Henrietta V.
Journal of Chemical Research, Miniprint, 1985 , # 12 p. 3830 - 3860
反应条件
1: 2) hydrated FeCl3 / 1) HMPA, 120 deg C, 3 h, 2) aq.HCl, 70 deg C, 20 min 2: 76 percent / 70percent aq.H2SO4 / 2 h / Heating View Scheme
参考文献
Ellis, Gwynn P.; Hudson, Henrietta V.
Journal of Chemical Research, Miniprint, 1985 , # 12 p. 3830 - 3860
反应条件
1: 300 °C 2: Raney nickel; methanol; ethanol / Hydrogenation View Scheme
参考文献
Naylor et al.
Journal of the Chemical Society, 1958 , p. 1190,1192
反应条件
1: 300 °C
2: Raney nickel; methanol; ethanol / Hydrogenation
3: ethanol; Raney nickel / Hydrogenation
View Scheme
参考文献
Naylor et al.
Journal of the Chemical Society, 1958 , p. 1190,1192
参考文献
Naylor et al.
Journal of the Chemical Society, 1958 , p. 1190,1192
