5-氟-1,3-二甲基尿嘧啶合成路线 （共 17 条）
反应条件
trifluoroacetic acid 10 h; Irradiation; Further byproducts given;
参考文献
Ohkura; Seki
Chemical and Pharmaceutical Bulletin, 1995 , vol. 43, # 6 p. 1024 - 1027
反应条件
1-methylguanidine hydrochloride; sodium in ethanol 6 h; Heating;
参考文献
Kheifets; Gindin; Studentsov
Russian Journal of Organic Chemistry, 2006 , vol. 42, # 4 p. 580 - 590
反应条件
sodium hydroxide; tetrabutylammomium bromide in dichloromethane
T=20°C; 48 h;
参考文献
Hedayatullah, Mir
Journal of Heterocyclic Chemistry, 1981 , vol. 18, p. 339 - 342
反应条件
potassium carbonate; 18-crown-6 ether in N,N-dimethyl-formamide
T=90°C; 15 h;
参考文献
Jansen, Helmut in de Wal; Lissel, Manfred
Zeitschrift fuer Naturforschung, B: Chemical Sciences, 1989 , vol. 44, # 7 p. 863 - 865
反应条件
CsSO4F; triethylamine in water
Ambient temperature;
参考文献
Stavber, Stojan; Zupan, Marko
Journal of the Chemical Society, Chemical Communications, 1983 , # 10 p. 563 - 564
反应条件
potassium carbonate in acetone
T=60 - 70°C; 24 h;
参考文献
Ishikawa; Itoh; Takayanagi; Oshima; Kawahara; Mizuno; Ogura
Chemical and Pharmaceutical Bulletin, 1991 , vol. 39, # 8 p. 1922 - 1930
反应条件
sodium hydroxide; water
Methylation; 1 h;
参考文献
Pelissier, Helene; Rodriguez, Jean; Vollhardt, K. Peter C.
Chemistry - A European Journal, 1999 , vol. 5, # 12 p. 3549 - 3561
反应条件
sulfur(IV) fluoride
T=-60°C; 48 h;
参考文献
Skulski, Lech; Kujawa, Anna; Wroczynski, Piotr
Bulletin of the Polish Academy of Sciences, Chemistry, 1991 , vol. 39, # 1 p. 23 - 28
反应条件
1: CsSO4F
2: CsSO4F / methanol
View Scheme
参考文献
Stavber, Stojan; Zupan, Marko
Journal of Fluorine Chemistry, 1983 , vol. 23, p. 487
反应条件
in xylene
6 h; Heating;
参考文献
Iwaoka; Murohashi; Sato; Kaneko
Synthesis, 1992 , # 10 p. 977 - 981
