二(三甲基硅烷基)亚膦酸酯合成路线 （共 15 条）
反应条件
T=-70°C; Title compound not separated from byproducts;
参考文献
Livantsov, M. V.; Prishchenko, A. A.; Lutsenko, I. F.
J. Gen. Chem. USSR (Engl. Transl.), 1985 , vol. 55, # 7 p. 1643 - 1644,1461 - 1462
反应条件
(i) 3,3-dimethyl-2-oxo-butyric acid methyl ester, (ii) /BRN= 636131/; Multistep reaction;
参考文献
Pudovik,A.N. et al.
J. Gen. Chem. USSR (Engl. Transl.), 1975 , vol. 45, p. 1896 - 1897,1858 - 1859
反应条件
1: in dichloromethane
T=25°C; 12 h;
2: With hydrogenchloride in methanol
0.25 h; Heating; Further stages.;
参考文献
Li, Shunzi; Whitehead, John K.; Hammer, Robert P.
Journal of Organic Chemistry, 2007 , vol. 72, # 8 p. 3116 - 3118
反应条件
1: in dichloromethane
T=0 - 20°C; 14 h; Inert atmosphere;
2: With hydrogenchloride in tetrahydrofuran; water
T=0 - 20°C; 2 h;
参考文献
Markoulides, Marios S.; Regan, Andrew C.
Organic and Biomolecular Chemistry, 2013 , vol. 11, # 1 p. 119 - 129
参考文献
Pudovik,A.N. et al.
J. Gen. Chem. USSR (Engl. Transl.), 1977 , vol. 47, p. 555 - 559,509 - 512
