3-[3-(4-氯苯基)-1,2,4-噁二唑]丙酸合成路线 （共 4 条）
反应条件
1: para-chloro-benzonitrile With hydroxylamine hydrochloride; sodium carbonate in methanol; water T=65°C; 2: succinic acid anhydride in N,N-dimethyl-formamide T=148°C; 0.5 h;
参考文献
Bioorganic and Medicinal Chemistry, , vol. 21, # 23 p. 7481 - 7498
参考文献
Srivastava; Borges Viana de; Bieber
Journal of Heterocyclic Chemistry, 1984 , vol. 21, # 4 p. 1193 - 1195
反应条件
T=140°C; 0.0333333 h; Microwave irradiationSealed vessel;
参考文献
Neves Filho, Ricardo Antonio Wanderley; Da Silva, Cecilia Aguiar; Da Silva, Clecia Sipriano Borges; Brustein, Vanessa Passos; Navarro, Daniela Maria Do Amaral Ferraz; Dos Santos, Fabio Andre Brayner; Alves, Luiz Carlos; Cavalcanti, Marilia Gabriela Dos Santos; Srivastava, Rajendra Mohan; Carneiro-Da-Cunha, Maria Das Gracas
Chemical and Pharmaceutical Bulletin, 2009 , vol. 57, # 8 p. 819 - 825
反应条件
1: Na2CO3; NH2OH*HCl / ethanol; H2O / Heating 2: Heating View Scheme
参考文献
Heterocycles, , vol. 51, # 12 p. 2961 - 2967
