2-甲基-3-喹啉羧酸甲酯合成路线 （共 22 条）
反应条件
1: 79 percent Chromat. / 50percent aq. sodium hydroxide / 0.5 h / Ambient temperature
2: 62 percent / hydrogen chloride / H2O / 1 h / Heating
View Scheme
参考文献
Hamada, Yoshiki; Sugiura, Michiharu; Hirota, Minoru
Tetrahedron Letters, 1981 , vol. 22, # 30 p. 2893 - 2894
反应条件
hydrogenchloride in ethanol
1 h;
参考文献
Hamada, Yoshiki; Sugiura, Michiharu; Hirota, Minoru
Tetrahedron Letters, 1981 , vol. 22, # 30 p. 2893 - 2894
反应条件
hydrogenchloride in methanol; water
1 h; Heating;
参考文献
Hamada, Yoshiki; Sugiura, Michiharu; Hirota, Minoru
Tetrahedron Letters, 1981 , vol. 22, # 30 p. 2893 - 2894
反应条件
hydrogenchloride; zinc in ethanol
0.5 h; Heating;
参考文献
Goerlitzer; Buss
Archiv der Pharmazie, 1981 , vol. 314, # 11 p. 938 - 949
反应条件
hydrogenchloride in methanol; water
1 h; Heating;
参考文献
Hamada, Yoshiki; Sugiura, Michiharu; Hirota, Minoru
Tetrahedron Letters, 1981 , vol. 22, # 30 p. 2893 - 2894
反应条件
1: 68 percent / Fe; aq. HCl
2: 92 percent / piperidine / methanol
View Scheme
参考文献
Nourry, Arnaud; Legoupy, Stephanie; Huet, Francois
Tetrahedron Letters, 2007 , vol. 48, # 34 p. 6014 - 6018
反应条件
1: 62 percent / 5 h / 100 °C
2: 9.4 percent / 10percent aq.HCl, Zn / ethanol / 0.5 h / Heating
View Scheme
参考文献
Goerlitzer; Buss
Archiv der Pharmazie, 1981 , vol. 314, # 11 p. 938 - 949
反应条件
in benzene
T=80°C; Friedlaender Quinoline Synthesis; 12 h; Solvent;
参考文献
Nammalwar, Baskar; Murie, Maeghan; Fortenberry, Chelsea; Bunce, Richard A.
Tetrahedron Letters, 2014 , vol. 55, # 20 p. 3181 - 3183
反应条件
sulfuric acid
1 h; Heating;
参考文献
Kiselyov, Alexander S.; Semenova, Marina; Semenov, Victor V.; Milligan, Daniel
Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 7 p. 1913 - 1919
参考文献
Claus; Steinitz
Justus Liebigs Annalen der Chemie, 1894 , vol. 282, p. 117 Anm.
