1-溴-2-甲基-1-丙烯合成路线 （共 93 条）
反应条件
CuI; potassium carbonate in ethyl acetate; toluene
参考文献
Buchwald, Stephen L.; Klapars, Artis; Antilla, Jon C.; Job, Gabriel E.; Wolter, Martina; Kwong, Fuk Y.; Nordmann, Gero; Hennessy, Edward J.
Patent: US2003/65187 A1, 2003 ;
反应条件
copper(l) iodide; potassium carbonate; N-methyl-2-(methylamino)ethylamine in toluene
T=90°C; 22 h;
参考文献
Jiang, Lei; Job, Gabriel E.; Klapars, Artis; Buchwald, Stephen L.
Organic Letters, 2003 , vol. 5, # 20 p. 3667 - 3669
反应条件
1: 1-bromo-2-methyl-1-propene With magnesium in tetrahydrofuran
2: 1-bromocyclohexane With N,N,N',N,-tetramethylethylenediamine; 1,3,5,7-tetra-azatricyclo[5.1.1.13,5]decane; iron (III) acetylacetonate in tetrahydrofuran
T=0°C; 1.5 h; Further stages.;
参考文献
Cahiez, Gerard; Duplais, Christophe; Moyeux, Alban
Organic Letters, 2007 , vol. 9, # 17 p. 3253 - 3254
反应条件
1: 1-bromo-2-methyl-1-propene With magnesium in tetrahydrofuran
2: 1-trans-IODO-4-CYCLOHEXYL With N,N,N',N,-tetramethylethylenediamine; 1,3,5,7-tetra-azatricyclo[5.1.1.13,5]decane; iron (III) acetylacetonate in tetrahydrofuran
T=0°C; 1.5 h; Further stages.;
参考文献
Cahiez, Gerard; Duplais, Christophe; Moyeux, Alban
Organic Letters, 2007 , vol. 9, # 17 p. 3253 - 3254
反应条件
1-methyl-pyrrolidin-2-one; iron (III) acetylacetonate in tetrahydrofuran
T=-5 - 0°C; 0.25 h;
参考文献
Cahiez, Gerard; Avedissian, Hovsep
Synthesis, 1998 , # 8 p. 1199 - 1205
反应条件
1: 1-bromo-2-methyl-1-propene With magnesium in tetrahydrofuran
2: cyclohexyl monochloride With N,N,N',N,-tetramethylethylenediamine; 1,3,5,7-tetra-azatricyclo[5.1.1.13,5]decane; iron (III) acetylacetonate in tetrahydrofuran
T=0°C; 1.5 h; Further stages.;
参考文献
Cahiez, Gerard; Duplais, Christophe; Moyeux, Alban
Organic Letters, 2007 , vol. 9, # 17 p. 3253 - 3254
反应条件
pyridine; quinoline
T=200°C;
参考文献
Adams; Ferretti
Journal of the American Chemical Society, 1959 , vol. 81, p. 4927,4929
参考文献
Butlerow
Zeitschrift fuer Chemie, 1870 , p. 524
反应条件
dinitrogen tetraoxide in diethyl ether
参考文献
Vasil'ev,S.V.; Burdelev,O.T.
Zhurnal Organicheskoi Khimii, 1966 , vol. 2, p. 1961 - 1965,1927 - 1930
反应条件
copper(l) iodide; magnesium
1.) THF, 2.) ether, -50 deg C, 3.) -50 to 25 deg C; Yield given. Multistep reaction;
参考文献
Mori, Kenji; Okada, Katsuhide
Tetrahedron, 1985 , vol. 41, # 3 p. 557 - 559
