4-(4-(苯并[d][1,3]二氧代l-5-基)-5-(吡啶-2-基)-1H-咪唑-2-基)苯甲酸合成路线 （共 2 条）
反应条件
hydrogenchloride 36 h; Heating;
参考文献
Smithkline Beecham Corporation
Patent: US6465493 B1, 2002 ;
反应条件
1: NH4OAc / acetic acid / 36 h / Heating 2: P(OEt)3 / dimethylformamide / 1 h / 110 °C 3: conc. HCl / 36 h / Heating View Scheme
参考文献
Callahan, James F.; Burgess, Joelle L.; Fornwald, James A.; Gaster, Laramie M.; Harling, John D.; Harrington, Frank P.; Heer, Jag; Kwon, Chet; Lehr, Ruth; Mathur; Olson, Barbara A.; Weinstock, Joseph; Laping, Nicholas J.
Journal of Medicinal Chemistry, 2002 , vol. 45, # 5 p. 999 - 1001
