1-苯-1H-吡咯-2-甲醛合成路线 （共 17 条）
反应条件
trichlorophosphate in 1,2-dichloro-ethane 0.0833333 h; HeatingIrradiation;
参考文献
Dumoulin, H.; Rault, S.; Robba, M.
Journal of Heterocyclic Chemistry, 1995 , vol. 32, # 6 p. 1703 - 1707
反应条件
sodium hydroxide; trichlorophosphate in dichloromethane; N,N-dimethyl-formamide
参考文献
Basell Technology Company BV
Patent: US6444833 B1, 2002 ;
反应条件
1: N,N-dimethyl-formamide With trichlorophosphate 0.166667 h; 2: 1-phenyl-1H-pyrrole in dichloromethane T=50°C; 1 h; 3: With sodium hydroxide in dichloromethane T=85 - 90°C; 0.166667 h; Further stages. Title compound not separated from byproducts.;
参考文献
Ilyin, Petrv.; Pankova, Alenas.; Kuznetsov, Mikhail A.
Synthesis, 2012 , vol. 44, # 9 p. 1353 - 1358
反应条件
potassium phosphate; copper(l) iodide; N,N'-dimethylcyclohexane-1,2-diamine in toluene T=110°C; 24 h;
参考文献
Antilla, Jon C.; Baskin, Jeremy M.; Barder, Timothy E.; Buchwald, Stephen L.
Journal of Organic Chemistry, 2004 , vol. 69, # 17 p. 5578 - 5587
反应条件
copper diacetate; triethylamine in dichloromethane T=20°C; 18 h;
参考文献
Purkarthofer, Thomas; Gruber, Karl; Fechter, Martin H.; Griengl, Herfried
Tetrahedron, 2005 , vol. 61, # 32 p. 7661 - 7668
反应条件
ethanol T=35 - 40°C; 72 h;
参考文献
Defoin; Geffroy; Le Nouen; Spileers; Streith
Helvetica Chimica Acta, 1989 , vol. 72, # 6 p. 1199 - 1215
反应条件
1,4-diaza-bicyclo[2.2.2]octane; oxygen; copper(II) bis(trifluoromethanesulfonate) T=100°C; P=760.051 Torr;
参考文献
Wang, Yi-Feng; Zhang, Feng-Lian; Chiba, Shunsuke
Synthesis, 2012 , vol. 44, # 10 p. 1526 - 1534
反应条件
1: N,N'-diphenylformamidine With trichlorophosphate in anhydrous dichloroethane Vilsmeier-Haack reaction; Reflux; 2: 1-phenyl-1H-pyrrole in anhydrous dichloroethane Vilsmeier-Haack reaction; 2 h; Reflux; 3: With water; sodium acetate regioselective reaction;
参考文献
Ilyin, Petrv.; Pankova, Alenas.; Kuznetsov, Mikhail A.
Synthesis, 2012 , vol. 44, # 9 p. 1353 - 1358
反应条件
1: 92 percent / AcOH / 0.08 h / Heating; Irradiation 2: 87 percent / POCl3 / 1,2-dichloro-ethane / 0.08 h / Heating; Irradiation View Scheme
参考文献
Dumoulin, H.; Rault, S.; Robba, M.
Journal of Heterocyclic Chemistry, 1995 , vol. 32, # 6 p. 1703 - 1707
反应条件
1: With trichlorophosphate in anhydrous dichloroethane Vilsmeier-Haack reaction; 1 h; Reflux; 2: With potassium hydroxide in anhydrous dichloroethane; water 0.0166667 h;
参考文献
Ilyin, Petrv.; Pankova, Alenas.; Kuznetsov, Mikhail A.
Synthesis, 2012 , vol. 44, # 9 p. 1353 - 1358
