2-(4-(嘧啶-2-基)哌嗪-1-基)乙胺合成路线 （共 4 条）
反应条件
hydrogen in methanol P=3102.97 Torr; 12 h; Autoclave;
参考文献
Ghosh, Balaram; Antonio, Tamara; Gopishetty, Bhaskar; Reith, Maarten; Dutta, Aloke
Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 15 p. 5661 - 5674
反应条件
potassium carbonate in hydrazine hydrate; N,N-dimethyl-formamide
参考文献
Neurogen Corporation
Patent: US5972945 A1, 1999 ;
US 5972945 A
反应条件
hydrazine in ethanol T=70°C; 5 h;
参考文献
Jung, Hee Kyung; Doddareddy, Munikumar Reddy; Cha, Joo Hwan; Rhim, Hyewhon; Cho, Yong Seo; Koh, Hun Yeong; Jung, Bong Young; Pae, Ae Nim
Bioorganic and Medicinal Chemistry, 2004 , vol. 12, # 15 p. 3965 - 3970
反应条件
1: K2CO3 / dimethylformamide / 2 h / 80 °C 2: hidrazine / ethanol / 5 h / 70 °C View Scheme
参考文献
Jung, Hee Kyung; Doddareddy, Munikumar Reddy; Cha, Joo Hwan; Rhim, Hyewhon; Cho, Yong Seo; Koh, Hun Yeong; Jung, Bong Young; Pae, Ae Nim
Bioorganic and Medicinal Chemistry, 2004 , vol. 12, # 15 p. 3965 - 3970
