4-氯-6-甲基吡啶-2-甲酸合成路线 （共 4 条）
反应条件
hydrogenchloride T=100°C; 2 h;
参考文献
Guery, Sebastien; Rival, Yveline; Wermuth, Camille G.
Synthetic Communications, 2002 , vol. 32, # 11 p. 1715 - 1719
反应条件
1.1: dimethyl sulfate / 1 h / 70 °C 1.2: 50 percent / H2O / 0 - 20 °C 2.1: 90 percent sulfuric acid / H2O / 2 h / 120 °C 2.2: 91 percent / sodium nitrite / H2O / 2 h / 20 - 80 °C 3.1: 80 percent / 37 percent hydrochloric acid / 2 h / 100 °C View Scheme
参考文献
Synthetic Communications, , vol. 32, # 11 p. 1715 - 1719
反应条件
1.1: 90 percent sulfuric acid / H2O / 2 h / 120 °C 1.2: 91 percent / sodium nitrite / H2O / 2 h / 20 - 80 °C 2.1: 80 percent / 37 percent hydrochloric acid / 2 h / 100 °C View Scheme
参考文献
Synthetic Communications, , vol. 32, # 11 p. 1715 - 1719
反应条件
potassium permanganate
参考文献
Journal of the Chemical Society, , vol. 67, p. 408
