2-溴-9,9-二辛基芴合成路线 （共 11 条）
反应条件
TEBAC; sodium hydroxide in dimethyl sulfoxide T=120°C;
参考文献
Poriel, Cyril; Rault-Berthelot, Joelle; Thirion, Damien; Barriere, Frederic; Vignau, Laurence
Chemistry - A European Journal, 2011 , vol. 17, # 50 p. 14031 - 14046
反应条件
1: 2-Bromofluorene With sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride in water; dimethyl sulfoxide T=20°C; 2 h; 2: 1-bromo-octane in water; dimethyl sulfoxide 2 h;
参考文献
3M Innovative Properties Company
Patent: US7094902 B2, 2006 ;
Location in patent: Page/Page column 89 ;
反应条件
1: With n-butyllithium in tetrahydrofuran; hexane T=0°C; 2: With methanol in tetrahydrofuran; hexane T=0°C;
参考文献
Nagaki, Aiichiro; Takabayashi, Naofumi; Tomida, Yutaka; Yoshida, Jun-Ichi
Beilstein Journal of Organic Chemistry, 2009 , vol. 5, art. no. A16
反应条件
1: in tetrahydrofuran; hexane T=0°C; 0.166667 h; 2: With methanol in tetrahydrofuran; hexane T=-78°C; 0.166667 h;
参考文献
Nagaki, Aiichiro; Takabayashi, Naofumi; Tomida, Yutaka; Yoshida, Jun-ichi
Organic Letters, 2008 , vol. 10, # 18 p. 3937 - 3940
反应条件
1: With n-butyllithium in tetrahydrofuran; hexane T=0°C; 1.58333E-05 h; flow conditions; 2: With methanol in tetrahydrofuran; hexane T=0°C; flow conditions;
参考文献
Nagaki, Aiichiro; Takabayashi, Naofumi; Tomida, Yutaka; Yoshida, Jun-Ichi
Beilstein Journal of Organic Chemistry, 2009 , vol. 5, art. no. A16
反应条件
1: With n-butyllithium in tetrahydrofuran; hexane T=0°C; 0.166667 h; 2: With methanol in tetrahydrofuran; hexane 0.166667 h;
参考文献
Nagaki, Aiichiro; Takabayashi, Naofumi; Tomida, Yutaka; Yoshida, Jun-Ichi
Beilstein Journal of Organic Chemistry, 2009 , vol. 5, art. no. A16
反应条件
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate in dimethyl sulfoxide T=80°C; 19 h; Inert atmosphere;
参考文献
Wang, Yafei; Tan, Hua; Liu, Yu; Jiang, Chenxian; Hu, Zhengyong; Zhu, Meixiang; Wang, Lei; Zhu, Weiguo; Cao, Yong
Tetrahedron, 2010 , vol. 66, # 7 p. 1483 - 1488
反应条件
1: 2-bromo-9,9-dioctyl-9H-fluorene With n-butyllithium in tetrahydrofuran; hexane T=-78°C; Metallation; 2: 2-isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane in tetrahydrofuran; hexane T=20°C; Substitution; 24 h; Further stages.;
参考文献
Belletete, Michel; Beaupre, Serge; Bouchard, Jimmy; Blondin, Pierre; Leclerc, Mario; Durocher, Gilles
Journal of Physical Chemistry B, 2000 , vol. 104, # 39 p. 9118 - 9125
反应条件
1: 2-bromo-9,9-dioctyl-9H-fluorene With n-butyllithium in tetrahydrofuran 2: iPrB(pinacolate) in tetrahydrofuran
参考文献
Cocherel, Nicolas; Poriel, Cyril; Rault-Berthelot, Joelle; Barriere, Frederic; Audebrand, Nathalie; Slawin, Alexandra M. Z.; Vignau, Laurence
Chemistry - A European Journal, 2008 , vol. 14, # 36 p. 11328 - 11342
反应条件
1: With n-butyllithium; tri-isopropoxy-borane in diethyl ether
2: With hydrogenchloride in water
Further stages.;
参考文献
Brownstein, Sydney K.; Ding, Jianfu; Robertson, Gilles; Roovers, Jacques; Enright, Gary
Journal of Organic Chemistry, 2002 , vol. 67, # 3 p. 663 - 667
