4-溴-5-氯-2-甲基苯胺合成路线 （共 2 条）
反应条件
1: With bromine; acetic acid T=10 - 20°C; 2: With sodium hydrogencarbonate in ethyl acetate
参考文献
Bayer Schering Pharma Aktiengesellschaft
Patent: US2010/105673 A1, 2010 ;
Location in patent: Page/Page column 12 ;
US 20100105673 A1
反应条件
1: With caesium carbonate in N,N-dimethyl-formamide T=25°C; 2: With palladium diacetate; triphenylphosphine T=120°C; 2 h;
参考文献
Gloeckner, Christian; Garner, Amanda L.; Mersha, Fana; Oksov, Yelena; Tricoche, Nancy; Eubanks, Lisa M.; Lustigman, Sara; Kaufmann, Gunnar F.; Janda, Kim D.
Proceedings of the National Academy of Sciences of the United States of America, 2010 , vol. 107, # 8 p. 3424 - 3429
