in tetrahydrofuran T=-45 - -40°C; Bartoli reaction;

1: in tetrahydrofuran T=-55°C; 1 h; 2: With water; ammonium chloride in tetrahydrofuran

2,2'-azo-bisisobutyronitrile; tri-n-butyl-tin hydride in toluene T=110°C; 12 h;

1: 7-bromo-2-methyl-1H-indole With potassium hydride in diethyl ether T=20°C; Rapoport synthesis; 1 h; Inert atmosphere; 2: With tert.-butyl lithium in diethyl ether; pentane T=-90 - 20°C; Rapoport synthesis; 2.5 h; Inert atmosphere; 3: N,N-dimethyl-formamide in diethyl ether; pentane Inert atmosphere;